The psychedelic effects of some plants and fungi have been known and deliberately
exploited by humans for thousands of years. Fungi, particularly mushrooms, are the principal …

This paper formulates the action of psychedelics by integrating the free-energy principle and
entropic brain hypothesis. We call this formulation relaxed beliefs under psychedelics …

Rationale A general feeling of disconnection has been associated with mental and
emotional suffering. Improvements to a sense of connectedness to self, others and the wider …

No contemporary unifying framework has been provided for the study of non-ordinary states
of consciousness (NSCs) despite increased interest in hypnosis, meditation, and …

Rationale Psychedelic research continues to garner significant public and scientific interest
with a growing number of clinical studies examining a wide range of conditions and …

The use of low sub-perceptual doses of psychedelics (“microdosing”) has gained popularity
in recent years. Although anecdotal reports claim multiple benefits associated with this …

Objective To conduct a systematic review of modern‐era (post‐millennium) clinical studies
assessing the therapeutic effects of serotonergic psychedelics drugs for mental health …

Previous studies have investigated challenging, difficult, or distressing classic psychedelic
experiences, but little is known about the prevalence and associations of such experiences …

The psychedelic psilocybin is being investigated for the treatment of depression and anxiety.
Unclear is whether antidepressant treatments interact with psilocybin. The present study …

Psychedelic drugs are increasingly being incorporated into therapeutic contexts for the
purposes of promoting mental health. However, they can also induce adverse reactions in …