Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most successful modern
pathogens. The same organism that lives as a commensal and is transmitted in both health …

Strains of bacteria resistant to antibiotics, particularly those that are multiresistant, are an
increasing major health care problem around the world. It is now abundantly clear that both …

Staphylococcus aureus, a major human pathogen, has a collection of virulence factors and
the ability to acquire resistance to most antibiotics. This ability is further augmented by …

The evolution of Staphylococcus aureus during the modern antibiotic era has been
delineated by distinct strain emergence events, many of which include acquisition of …

Staphylococcus aureus is capable of becoming resistant to all classes of antibiotics clinically
available and resistance can develop through de novo mutations in chromosomal genes or …

Microbial pathogenesis studies are typically performed with reference strains, thereby
overlooking within-species heterogeneity in microbial virulence. Here we integrated human …

Bacterial skin infections represent some of the most common infectious diseases globally.
Prevention and treatment of skin infections can involve application of a topical antimicrobial …

Increasing attention has been focused on understanding bacterial biofilms and this growth
modality's relation to human disease. In this review we explore the genetic regulation and …

Staphylococcus aureus is an important cause of skin and soft-tissue infections (SSTIs),
endovascular infections, pneumonia, septic arthritis, endocarditis, osteomyelitis, foreign …

Staphylococcus aureus produces a wide variety of toxins including staphylococcal
enterotoxins (SEs; SEA to SEE, SEG to SEI, SER to SET) with demonstrated emetic activity …