Background Intravenous fluids and vasopressor agents are commonly used in early
resuscitation of patients with sepsis, but comparative data for prioritizing their delivery are …

The regulation of body fluid balance is a key concern in health and disease and comprises
three concepts. The first concept pertains to the relationship between total body water (TBW) …

BACKGROUND: Positive fluid balance has been associated with worse outcomes, and
knowledge of differences in the amounts of different types of fluid needed to achieve the …

Abstract Background The previously published “Dose Response Multicentre International
Collaborative Initiative (DoReMi)” study concluded that the high mortality of critically ill …

Objectives: Among critically ill patients with acute kidney injury, exposure to positive fluid
balance, compared with negative fluid balance, has been associated with mortality and …

Introduction Sepsis and septic shock continue to be syndromes that carry a high mortality
rate worldwide. Early aggressive fluid and vasopressor support have resulted in significant …

Introduction Acute respiratory distress syndrome (ARDS) is characterized by acute, diffuse,
inflammatory lung injury leading to increased pulmonary vascular permeability, pulmonary …

Objective Positive fluid balance is common among critically ill patients and leads to worse
outcomes, particularly in sepsis, acute respiratory distress syndrome, and acute kidney …

Fluids are considered the cornerstone of therapy for many shock states, particularly states
that are associated with relative or absolute hypovolemia. Fluids are also commonly used for …

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