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Encapsulation and assessment of therapeutic cargo in engineered exosomes: a systematic review
Z Chen, M **ong, J Tian, D Song, S Duan… - Journal of …, 2024 - Springer
Exosomes are nanoscale extracellular vesicles secreted by cells and enclosed by a lipid
bilayer membrane containing various biologically active cargoes such as proteins, lipids …
bilayer membrane containing various biologically active cargoes such as proteins, lipids …
A comprehensive review of engineered exosomes from preparation strategy to therapy applications
X Fan, Y Zhang, W Liu, M Shao, Y Gong, T Wang… - Biomaterials …, 2024 - pubs.rsc.org
Exosomes exhibit high bioavailability, biological stability, targeted specificity, low toxicity,
and low immunogenicity in shuttling various bioactive molecules such as proteins, lipids …
and low immunogenicity in shuttling various bioactive molecules such as proteins, lipids …
Genetically engineered loaded extracellular vesicles for drug delivery
The use of extracellular vesicles (EVs) for drug delivery is being widely explored by
scientists from several research fields. To fully exploit their therapeutic potential, multiple …
scientists from several research fields. To fully exploit their therapeutic potential, multiple …
Advances in Extracellular-Vesicles-Based Diagnostic and Therapeutic Approaches for Ocular Diseases
Y Su, M Chen, W Xu, P Gu, X Fan - ACS nano, 2024 - ACS Publications
Extracellular vesicles (EVs) are nanoscale membrane vesicles of various sizes that can be
secreted by most cells. EVs contain a diverse array of cargo, including RNAs, lipids …
secreted by most cells. EVs contain a diverse array of cargo, including RNAs, lipids …
Enhanced therapeutic efficacy against melanoma through exosomal delivery of hesperidin
Melanoma, characterized as the most aggressive and metastatic form of skin cancer,
currently has limited treatment options, predominantly chemotherapy and radiation therapy …
currently has limited treatment options, predominantly chemotherapy and radiation therapy …
Exosomes for neurodegenerative diseases: diagnosis and targeted therapy
H Tao, B Gao - Journal of Neurology, 2024 - Springer
Abstract Purpose of Review Neurodegenerative diseases are still challenging clinical
issues, with no curative interventions available and early, accurate diagnosis remaining …
issues, with no curative interventions available and early, accurate diagnosis remaining …
[HTML][HTML] Fluorescence tracking of small extracellular vesicles in vivo
Y Chen, Y Shi, Z Tao - Pharmaceutics, 2023 - mdpi.com
In this study, we employed organic and inorganic dyes that have fluorescence under visible
or near-infrared light region to stain human umbilical cord (Huc) mesenchymal stem cell …
or near-infrared light region to stain human umbilical cord (Huc) mesenchymal stem cell …
Functionalized solid lipid nanoparticles combining docetaxel and erlotinib synergize the anticancer efficacy against triple-negative breast cancer
The goal of the study was to fabricate folic acid functionalized docetaxel (DOC)/erlotinib
(ERL)-loaded solid lipid nanoparticles (SLNs) to synergistically increase the anticancer …
(ERL)-loaded solid lipid nanoparticles (SLNs) to synergistically increase the anticancer …
[HTML][HTML] Combinatorial delivery of docetaxel-and erlotinib-loaded functionalized nanostructured lipid carriers for the treatment of triple-negative breast cancer using …
This study explored the combined administration of docetaxel (DOC) and erlotinib (ERL)
using nanostructured lipid carriers (NLCs), with folic acid (FA) conjugation to enhance their …
using nanostructured lipid carriers (NLCs), with folic acid (FA) conjugation to enhance their …
Application of exosomes as nanocarriers in cancer therapy
J Hu, J Zhu, J Chai, Y Zhao, J Luan… - Journal of Materials …, 2023 - pubs.rsc.org
Cancer remains the most common lethal disease in the world. Although the treatment
choices for cancer are still limited, significant progress has been made over the past few …
choices for cancer are still limited, significant progress has been made over the past few …