Neurofibromatosis type II (NF2) is a tumor predisposition syndrome characterized by the
development of distinctive nervous system lesions. NF2 results from loss-of-function …

Abstract Neurofibromatosis type 2 (NF2) is a genetic condition marked by the development
of multiple benign tumors in the nervous system. The most common tumors associated with …

Neurofibromatosis type 2 is an often devastating autosomal dominant disorder which, until
relatively recently, was confused with its more common namesake neurofibromatosis type 1 …

Adult spinal cord ependymomas are typically low grade and have a relatively favorable
clinical course following gross total resection. We report 4 cases of anaplastic spinal cord …

Objective Because clinically validated biomarkers for neurofibromatosis 1 (NF1) and
neurofibromatosis 2 (NF2) have not been identified, we aimed to determine whether …

Purpose We have evaluated deficiencies in existing diagnostic criteria for neurofibromatosis
2 (NF2). Methods Two large databases of individuals fulfilling NF2 criteria (n= 1361) and …

Background Radiation treatment of benign tumors in tumor predisposition syndromes is
controversial, but short-term studies from treatment centers suggest safety despite apparent …

Intramedullary spinal cord tumors (IMSCTs) comprise a rare subset of central nervous
system (CNS) tumors that can develop at any age and have distinct management strategies …

Genetic syndromes which develop one or more nervous system (NS) tumors as one of the
manifestations can be grouped under the umbrella term of NS tumor predisposition …

Simple Summary The neurofibromatoses—neurofibromatosis type 1, neurofibromatosis type
2, and schwannomatosis—are genetic tumor predisposition syndromes in which affected …