[HTML][HTML] Synthesis of antimicrobial benzimidazole–pyrazole compounds and their biological activities

M Marinescu - Antibiotics, 2021 - mdpi.com
The synthesis of new compounds with antimicrobial and antiviral properties is a central
objective today in the context of the COVID-19 pandemic. Benzimidazole and pyrazole …

Imidazole derivatives and their antibacterial activity-a mini-review

GŞ Andrei, BF Andrei… - Mini reviews in medicinal …, 2021 - ingentaconnect.com
Background: The development of drug resistance by bacterial strains is a public health
issue, being the main cause of the decrease in the effectiveness of numerous antibiotics. In …

Synthesis of benzimidazole‐sulfonyl derivatives and their biological activities

E Mulugeta, Y Samuel - Biochemistry Research International, 2022 - Wiley Online Library
Currently, the synthesis of new compounds with potential bioactivities has become a central
issue in the drug discovery arena. Among these new compounds, benzimidazole‐sulfonyl …

The medicinal panorama of benzimidazoles and their scaffolds as anticancer and antithrombotic agents: A review

PKB Chalkappa, S Aralihalli, M Sudileti… - Archiv der …, 2023 - Wiley Online Library
Nitrogen‐containing heterocyclic scaffolds have become a prospective pharmacophore with
therapeutic importance due to their biological similarities with natural and synthetic drugs …

Adsorption behavior and corrosion inhibitive characteristics of newly synthesized cyano-benzylidene xanthenes on copper/sodium hydroxide interface …

ME Khalifa, IH El Azab, AA Gobouri, GAM Mersal… - Journal of Colloid and …, 2020 - Elsevier
Elegant process for synthesis of 3-(7H-dibenzo [c, h] xanthen-7-yl) benzaldehyde (3), as
new starting material to create a set of novel xanthene analogues, 2-(3-(7 H-dibenzo [c, h] …

Gewald synthesis, antitumor profile and molecular modeling of novel 5-acetyl-4-((4-acetylphenyl) amino)-2-aminothiophene-3-carbonitrile scaffolds

ME Khalifa, WM Algothami - Journal of Molecular Structure, 2020 - Elsevier
Novel targets of 2-aminothiophene derivatives (2–9) were synthesized based upon
preparation of the newly 5-acetyl-4-((4-acetylphenyl) amino)-2-aminothiophene-3 …

Bioassay-and metabolomics-guided screening of bioactive soil actinomycetes from the ancient city of Ihnasia, Egypt

M Sebak, AE Saafan, S AbdelGhani, W Bakeer… - PLoS …, 2019 - journals.plos.org
Literature surveys, taxonomical differences, and bioassay results have been utilized in the
discovery of new natural products to aid in Actinomycetes isolate-selection. However, no or …

Synthesis of 1-(2-Hydroxyphenyl)-and (3, 5-Dichloro-2-hydroxyphenyl)-5-oxopyrrolidine-3-carboxylic Acid Derivatives as Promising Scaffolds for the Development of …

M Bertašiūtė, P Kavaliauskas, R Vaickelionienė… - International Journal of …, 2023 - mdpi.com
Increasing antimicrobial resistance among Gram-positive pathogens and pathogenic fungi
remains one of the major public healthcare threats. Therefore, novel antimicrobial …

Design, synthesis and molecular docking study of new purine derivatives as Aurora kinase inhibitors

ME Khalifa - Journal of Molecular Structure, 2021 - Elsevier
Nine new purine-based compounds were designed and have been synthesized through
series reactions of the starting compound 8-amino-substituted purine (2) with various …

[HTML][HTML] Design, molecular modeling and synthesis of metal-free sensitizers of thieno pyridine dyes as light-harvesting materials with efficiency improvement using …

ME Khalifa, ASA Almalki, A Merazga, GAM Mersal - Molecules, 2020 - mdpi.com
Considering the thiophene unit as an electron-rich heterocycle, it is investigated with the aim
of elucidating its potential efficiency for solar cell application. With the introduction of active …