ACTN3: More than Just a Gene for Speed

C Pickering, J Kiely - Frontiers in physiology, 2017 - frontiersin.org
Over the last couple of decades, research has focused on attempting to understand the
genetic influence on sports performance. This has led to the identification of a number of …

More than a 'speed gene': ACTN3 R577X genotype, trainability, muscle damage, and the risk for injuries

J Del Coso, D Hiam, P Houweling, LM Pérez… - European journal of …, 2019 - Springer
A common null polymorphism (rs1815739; R577X) in the gene that codes for α-actinin-3
(ACTN3) has been related to different aspects of exercise performance. Individuals who are …

A genome-wide association study of sprint performance in elite youth football players

C Pickering, B Suraci, EA Semenova… - The Journal of …, 2019 - journals.lww.com
Abstract Pickering, C, Suraci, B, Semenova, EA, Boulygina, EA, Kostryukova, ES, Kulemin,
NA, Borisov, OV, Khabibova, SA, Larin, AK, Pavlenko, AV, Lyubaeva, EV, Popov, DV …

Is evolutionary loss our gain? The role of ACTN3 p.Arg577Ter (R577X) genotype in athletic performance, ageing, and disease

PJ Houweling, ID Papadimitriou, JT Seto… - Human …, 2018 - Wiley Online Library
A common null polymorphism in the ACTN3 gene (rs1815739: C> T) results in replacement
of an arginine (R) with a premature stop codon (X) at amino acid 577 in the fast muscle …

[HTML][HTML] Association of genetic profile with muscle mass gain and muscle injury prevention in professional football players after creatine supplementation

D Varillas-Delgado - Nutrients, 2024 - mdpi.com
Background: In recent years, the study of creatine supplementation in professional athletes
has been of great interest. However, the genetics involved in response to supplementation is …

Genetic profile in genes associated with sports injuries in elite endurance athletes

D Varillas-Delgado, J Gutierrez-Hellín… - … journal of sports …, 2023 - thieme-connect.com
Injuries are a complex trait that can stem from the interaction of several genes. The aim of
this research was to examine the relationship between muscle performance-related genes …

ESR1 rs2234693 polymorphism is associated with muscle injury and muscle stiffness

H Kumagai, E Miyamoto-Mikami… - … and Science in …, 2018 - pmc.ncbi.nlm.nih.gov
Purpose Muscle injury is the most common sports injury. Muscle stiffness, a risk factor for
muscle injury, is lower in females than in males, implying that sex-related genetic …

Effect of ACTN3 Genotype on Sports Performance, Exercise-Induced Muscle Damage, and Injury Epidemiology

G Baltazar-Martins, J Gutiérrez-Hellín… - Sports, 2020 - mdpi.com
Genetic factors play a significant role in athletic performance and its related phenotypes
such as power, strength and aerobic capacity. In this regard, the lack of a muscle protein due …

Novel insights into mitochondrial DNA: mitochondrial microproteins and mtDNA variants modulate athletic performance and age-related diseases

H Kumagai, B Miller, SJ Kim, N Leelaprachakul… - Genes, 2023 - mdpi.com
Sports genetics research began in the late 1990s and over 200 variants have been reported
as athletic performance-and sports injuries-related genetic polymorphisms. Genetic …

The Genetic Association with Athlete Status, Physical Performance, and Injury Risk in Soccer

CF Murtagh, ECR Hall, TE Brownlee… - … Journal of Sports …, 2023 - thieme-connect.com
The aim of this review was to critically appraise the literature concerning the genetic
association with athlete status, physical performance, and injury risk in soccer. The …