Effects of ionizing radiation on biological molecules—mechanisms of damage and emerging methods of detection

JA Reisz, N Bansal, J Qian, W Zhao… - Antioxidants & redox …, 2014 - liebertpub.com
Significance: The detrimental effects of ionizing radiation (IR) involve a highly orchestrated
series of events that are amplified by endogenous signaling and culminating in oxidative …

Protein carbonylation as a major hallmark of oxidative damage: update of analytical strategies

M Fedorova, RC Bollineni… - Mass spectrometry …, 2014 - Wiley Online Library
Protein carbonylation, one of the most harmful irreversible oxidative protein modifications, is
considered as a major hallmark of oxidative stress‐related disorders. Protein carbonyl …

Biomarkers of lipid peroxidation in clinical material

E Niki - Biochimica et Biophysica Acta (BBA)-General Subjects, 2014 - Elsevier
Background Free radical-mediated lipid peroxidation has been implicated in a number of
human diseases. Diverse methods have been developed and applied to measure lipid …

Peptide profiling of bovine kefir reveals 236 unique peptides released from caseins during its production by starter culture or kefir grains

J Ebner, AA Arslan, M Fedorova, R Hoffmann… - Journal of …, 2015 - Elsevier
Kefir has a long tradition in human nutrition due to its presupposed health promoting effects.
To investigate the potential contribution of bioactive peptides to the physiological effects of …

Structural library and visualization of endogenously oxidized phosphatidylcholines using mass spectrometry-based techniques

Y Matsuoka, M Takahashi, Y Sugiura, Y Izumi… - Nature …, 2021 - nature.com
Although oxidized phosphatidylcholines (oxPCs) play critical roles in numerous pathological
events, the type and production sites of endogenous oxPCs remain unknown because of the …

Membrane oxidation in cell delivery and cell killing applications

TY Wang, MDJ Libardo, AM Angeles-Boza… - ACS chemical …, 2017 - ACS Publications
Cell delivery or cell killing processes often involve the crossing or disruption of cellular
membranes. We review how, by modifying the composition and properties of membranes …

A comprehensive review on source, types, effects, nanotechnology, detection, and therapeutic management of reactive carbonyl species associated with various …

S Fuloria, V Subramaniyan, S Karupiah, U Kumari… - Antioxidants, 2020 - mdpi.com
Continuous oxidation of carbohydrates, lipids, and amino acids generate extremely reactive
carbonyl species (RCS). Human body comprises some important RCS namely hexanal …

Near-infrared rechargeable “optical battery” implant for irradiation-free photodynamic therapy

L Hu, P Wang, M Zhao, L Liu, L Zhou, B Li… - Biomaterials, 2018 - Elsevier
As a minimal or noninvasive therapeutic method for tumors, photodynamic therapy (PDT)
induced by the external laser irradiations has attracted great attentions. However, the UV …

Options of the main derivatization approaches for analytical ESI and MALDI mass spectrometry

VG Zaikin, RS Borisov - Critical Reviews in Analytical Chemistry, 2022 - Taylor & Francis
The inclusion of preliminary chemical labeling (derivatization) in the analysis process by
such powerful and widespread methods as electrospray ionization (ESI) and matrix-assisted …

The structural integrity of the model lipid membrane during induced lipid peroxidation: The role of flavonols in the inhibition of lipid peroxidation

A Sadžak, J Mravljak, N Maltar-Strmečki, Z Arsov… - Antioxidants, 2020 - mdpi.com
The structural integrity, elasticity, and fluidity of lipid membranes are critical for cellular
activities such as communication between cells, exocytosis, and endocytosis. Unsaturated …