The contribution of environmental exposure to the etiology of autism spectrum disorder

S Bölte, S Girdler, PB Marschik - Cellular and Molecular Life Sciences, 2019 - Springer
Autism spectrum disorder (ASD) is a neurodevelopmental condition of heterogeneous
etiology. While it is widely recognized that genetic and environmental factors and their …

An overview of the main genetic, epigenetic and environmental factors involved in autism spectrum disorder focusing on synaptic activity

E Masini, E Loi, AF Vega-Benedetti, M Carta… - International journal of …, 2020 - mdpi.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder that affects social
interaction and communication, with restricted interests, activity and behaviors. ASD is highly …

[HTML][HTML] Sex/gender differences and autism: setting the scene for future research

MC Lai, MV Lombardo, B Auyeung… - Journal of the American …, 2015 - Elsevier
Objective The relationship between sex/gender differences and autism has attracted a
variety of research ranging from clinical and neurobiological to etiological, stimulated by the …

Measuring autistic traits in the general population: a systematic review of the Autism-Spectrum Quotient (AQ) in a nonclinical population sample of 6,900 typical adult …

E Ruzich, C Allison, P Smith, P Watson, B Auyeung… - Molecular autism, 2015 - Springer
Abstract The Autism-Spectrum Quotient (AQ) is a self-report measure of autistic traits. It is
frequently cited in diverse fields and has been administered to adults of at least average …

The role of estrogen receptors and their signaling across psychiatric disorders

WJ Hwang, TY Lee, NS Kim, JS Kwon - International journal of molecular …, 2020 - mdpi.com
Increasing evidence suggests estrogen and estrogen signaling pathway disturbances
across psychiatric disorders. Estrogens are not only crucial in sexual maturation and …

Machine learning in autistic spectrum disorder behavioral research: A review and ways forward

F Thabtah - Informatics for Health and Social Care, 2019 - Taylor & Francis
ABSTRACT Autistic Spectrum Disorder (ASD) is a mental disorder that retards acquisition of
linguistic, communication, cognitive, and social skills and abilities. Despite being diagnosed …

Oxytocin pathway genes: evolutionary ancient system impacting on human affiliation, sociality, and psychopathology

R Feldman, M Monakhov, M Pratt, RP Ebstein - Biological psychiatry, 2016 - Elsevier
Oxytocin (OT), a nonapeptide signaling molecule originating from an ancestral peptide,
appears in different variants across all vertebrate and several invertebrate species …

Toward brief “red flags” for autism screening: the short autism spectrum quotient and the short quantitative checklist in 1,000 cases and 3,000 controls

C Allison, B Auyeung, S Baron-Cohen - … of the American Academy of Child …, 2012 - Elsevier
OBJECTIVE: Frontline health professionals need a “red flag” tool to aid their decision
making about whether to make a referral for a full diagnostic assessment for an autism …

Toward a second-person neuroscience1

L Schilbach, B Timmermans, V Reddy… - Behavioral and brain …, 2013 - cambridge.org
In spite of the remarkable progress made in the burgeoning field of social neuroscience, the
neural mechanisms that underlie social encounters are only beginning to be studied and …

CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in cerebral organoids derived from iPS …

P Wang, R Mokhtari, E Pedrosa, M Kirschenbaum… - Molecular autism, 2017 - Springer
Background CHD8 (chromodomain helicase DNA-binding protein 8), which codes for a
member of the CHD family of ATP-dependent chromatin-remodeling factors, is one of the …