Gastric cancer is one of the most common cancers and has the highest mortality rate
worldwide. It is worthwhile to explore the mechanism of gastric cancer progression. An …

Knowledge of the fundamental epigenetic mechanisms governing gene expression and
cellular phenotype are sufficiently advanced that novel insights into the epigenetic control of …

Immune dysregulation plays a vital role in colorectal cancer initiation and progression. Long
noncoding RNAs (lncRNA) exhibit multiple functions including regulation of gene …

Hepatocellular carcinoma (HCC) is a devastating disease worldwide. Though many efforts
have been made to elucidate the process of HCC, its molecular mechanisms of …

Long noncoding RNAs (lncRNAs) are a class of non-protein-coding molecules longer than
200 nucleotides that are involved in the development and progression of many types of …

Background RNA-sequencing (RNA-seq) has emerged as one of the most sensitive tool for
gene expression analysis. Among the library preparation methods available, the standard …

Background: As one of the most common liver disorders worldwide, non-alcoholic fatty liver
disease (NAFLD) begins with the abnormal accumulation of triglyceride (TG) in the liver …

The colorectal neoplasia differentially expressed (CRNDE) gene encodes a long non-
coding RNA (lncRNA) that is the most unregulated among 129 lncRNAs differentially …

Liver cancer is the second leading cause of cancer-related death globally, with limited
treatment options. Recent studies have demonstrated the critical role of long noncoding …

Novel insights into the epigenetic control of chronic liver diseases are now emerging.
Recent advances in our understanding of the critical roles of DNA methylation, histone …