Parkinson's disease (PD) is a chronic neurodegenerative condition affecting more than 1%
of people over 65 years old. It is characterized by the preferential degeneration of …

The neurodegenerative process is characterized by the progressive ultrastructural
alterations of selected classes of neurons accompanied by imbalanced cellular …

This work aimed to evaluate the potential of the nanosystems constituted by dopamine (DA)
and the antioxidant Citicoline (CIT) co-loaded in solid lipid nanoparticles (SLNs) for …

Oxidative stress is a key mediator in the development and progression of Parkinson's
disease (PD). The antioxidant N-acetylcysteine (NAC) has generated interest as a disease …

The toxicity of accumulated α-synuclein plays a key role in the neurodegeneration of
Parkinson's disease (PD). This study has demonstrated that iron in varying concentrations …

The aging process impacts neural stem cells and causes a significant decline in
neurogenesis that contributes to neuronal dysfunction leading to cognitive decline …

Background: The blood–brain barrier (BBB) bypass of dopamine (DA) is still a challenge for
supplying it to the neurons of Substantia Nigra mainly affected by Parkinson disease. DA …

The development of neuroprotective drugs targeting mitochondria could be an important
strategy in combating the progressive clinical course of Parkinson's disease. In the current …

Aims Parkinson's disease (PD) is a common neurodegenerative disease typically
associated with the accumulation of α-synuclein. Autophagy impairment is thought to be …

The present study demonstrates the efficacies of synthetic 1, 8-cineole and an 1, 8-cineole-
rich supercritical carbon dioxide (SC-CO 2) extract of small cardamom seeds in preventing …