Nanoprobe-based molecular imaging for tumor stratification

X Ma, M Mao, J He, C Liang, HY **e - Chemical Society Reviews, 2023 - pubs.rsc.org
The responses of patients to tumor therapies vary due to tumor heterogeneity. Tumor
stratification has been attracting increasing attention for accurately distinguishing between …

Tumour-associated macrophages: versatile players in the tumour microenvironment

ZZ Ji, MKK Chan, ASW Chan, KT Leung… - Frontiers in Cell and …, 2023 - frontiersin.org
Tumour-Associated Macrophages (TAMs) are one of the pivotal components of the tumour
microenvironment. Their roles in the cancer immunity are complicated, both pro-tumour and …

Glucose oxidase driven hydrogen sulfide-releasing nanocascade for diabetic infection treatment

Y Ge, F Rong, Y Lu, Z Wang, J Liu, F Xu, J Chen… - Nano Letters, 2023 - ACS Publications
Diabetic ulcers have received much attention in recent years due to their high incidence and
mortality, motivating the scientific community to develop various strategies for such chronic …

Gut microbiota promotes macrophage M1 polarization in hepatic sinusoidal obstruction syndrome via regulating intestinal barrier function mediated by butyrate

S Zhao, H Zhang, H Zhu, T Zhao, J Tu, X Yin… - Gut …, 2024 - Taylor & Francis
Background The intestinal-liver axis is associated with various liver diseases. Here, we
verified the role of the gut microbiota and macrophage activation in the progression of …

A Cyclodextrin‐Based pH‐Responsive MicroRNA Delivery Platform Targeting Polarization of M1 to M2 Macrophages for Sepsis Therapy

N Ding, G Luo, H Li, C **ng, Y Gao, W **… - Advanced …, 2023 - Wiley Online Library
The mortality rate of sepsis remains high despite improvements in the diagnosis and
treatment of sepsis using symptomatic and supportive therapies, such as anti‐infection …

Molecular imaging of innate immunity and immunotherapy

W **a, N Singh, S Goel, S Shi - Advanced Drug Delivery Reviews, 2023 - Elsevier
The innate immune system plays a key role as the first line of defense in various human
diseases including cancer, cardiovascular and inflammatory diseases. In contrast to tissue …

NMN sensor cocktail: selective sensing of nicotinamide mononucleotide over citric acid

HG Lee, NK Hong, YT Chang - Chemical Communications, 2023 - pubs.rsc.org
The fluorescent probe pair, NBD-B2 and Styryl-51F, selectively detects NMN over citric acid.
NBD-B2 exhibits increased fluorescence, while Styryl-51F shows decreased fluorescence …

Targeting macrophage phenotypes and metabolism as novel therapeutic approaches in atherosclerosis and related cardiovascular diseases

J Wang, Q Wu, X Wang, H Liu, M Chen, L Xu… - Current Atherosclerosis …, 2024 - Springer
Purpose of the review Macrophage accumulation and activation function as hallmarks of
atherosclerosis and have complex and intricate dynamics throughout all components and …

[HTML][HTML] Dual-sided centripetal microgrooved poly (D, L-lactide-co-caprolactone) disk encased in immune-regulating hydrogels for enhanced bone regeneration

Y Wu, X Yue, Y Zhang, N Yu, C Ge, R Liu, Z Duan… - Materials Today Bio, 2025 - Elsevier
Well-designed artificial scaffolds are urgently needed due to the limited self-repair capacity
of bone, which hampers effective regeneration in critical defects. Optimal scaffolds must …

Visualizing macrophage phenotypes and polarization in diseases: from biomarkers to Molecular Probes

D Ni, H Zhou, P Wang, F Xu, C Li - Phenomics, 2023 - Springer
Macrophage is a kind of immune cell and performs multiple functions including pathogen
phagocytosis, antigen presentation and tissue remodeling. To fulfill their functionally distinct …