Cell–cell communication (CCC) is essential to how life forms and functions. However,
accurate, high-throughput map** of how expression of all genes in one cell affects …

Fibroblasts, custodians of tissue architecture and function, are no longer considered a
monolithic entity across tissues and disease indications. Recent advances in single‐cell …

Spatially resolved transcriptomics (SRT) provide gene expression close to, or even superior
to, single-cell resolution while retaining the physical locations of sequencing and often also …

While experimental and informatic techniques around single cell sequencing (scRNA-seq)
are advanced, research around mass cytometry (CyTOF) data analysis has severely lagged …

Numerous variants, including both single-nucleotide variants (SNVs) in DNA and A> G RNA
edits in mRNA as essential drivers of cellular proliferation and tumorigenesis, are commonly …

Immunotherapy has revolutionized cancer treatment and brought new aspects into tumor
immunology. Effective immunotherapy will require using the suitable target antigens …

Spatially resolved transcriptomics (SRT) combines gene expression profiles with the
physical locations of cells in their native states but suffers from unpredictable spatial noise …

Single-cell sequencing methodologies such as scRNA-seq and scATAC-seq have become
widespread and effective tools to interrogate tissue composition. Increasingly, variant callers …

Neoantigens are the key targets of antitumor immune responses from cytotoxic T cells and
play a critical role in affecting tumor progressions and immunotherapy treatment responses …

Background Gene expression is regulated by transcription factors, cofactors, and epigenetic
mechanisms. Coexpressed genes indicate similar functional categories and gene networks …