Type 2 diabetes

S Chatterjee, K Khunti, MJ Davies - The lancet, 2017 - thelancet.com
Summary 415 million people live with diabetes worldwide, and an estimated 193 million
people have undiagnosed diabetes. Type 2 diabetes accounts for more than 90% of patients …

Continuous glucose monitoring: a brief review for primary care practitioners

R Ajjan, D Slattery, E Wright - Advances in therapy, 2019 - Springer
Glycated hemoglobin A1c (HbA1c) is routinely used as a marker of average glycemic
control, but it fails to provide data on hypoglycemia and glycemic variability, both of which …

[HTML][HTML] Real-world flash glucose monitoring patterns and associations between self-monitoring frequency and glycaemic measures: a European analysis of over 60 …

TC Dunn, Y Xu, G Hayter, RA Ajjan - Diabetes Research and clinical …, 2018 - Elsevier
Aims Randomised controlled trials demonstrate that using flash glucose monitoring
improves glycaemic control but it is unclear whether this applies outside trial conditions. We …

Severe hypoglycemia requiring medical intervention in a large cohort of adults with diabetes receiving care in US integrated health care delivery systems: 2005–2011

RD Pathak, EB Schroeder, ER Seaquist, C Zeng… - Diabetes …, 2016 - Am Diabetes Assoc
OBJECTIVE Appropriate glycemic control is fundamental to diabetes care, but aggressive
glucose targets and intensive therapy may unintentionally increase episodes of …

Thrombosis and vascular inflammation in diabetes: mechanisms and potential therapeutic targets

N Pechlivani, RA Ajjan - Frontiers in cardiovascular medicine, 2018 - frontiersin.org
Cardiovascular disease remains the main cause of morbidity and mortality in patients with
diabetes. The risk of vascular ischemia is increased in this population and outcome …

Flash glucose monitoring reduces glycemic variability and hypoglycemia: real-world data from Spain

F Gomez-Peralta, T Dunn, K Landuyt, Y Xu… - BMJ Open Diabetes …, 2020 - drc.bmj.com
Objective Observations in real-world settings support and extend findings demonstrated in
randomized controlled trials that show flash glucose monitoring improves glycemic control …

Multicenter randomized trial of intermittently scanned continuous glucose monitoring versus self-monitoring of blood glucose in individuals with type 2 diabetes and …

RA Ajjan, SR Heller, CC Everett… - Diabetes …, 2023 - Am Diabetes Assoc
OBJECTIVE To analyze the impact of modern glucose-monitoring strategies on glycemic
and patient-related outcomes in individuals with type 2 diabetes (T2D) and recent …

How can we realize the clinical benefits of continuous glucose monitoring?

RA Ajjan - Diabetes technology & therapeutics, 2017 - liebertpub.com
Controlling glycemia in diabetes remains key to prevent complications in this condition.
However, glucose levels can undergo large fluctuations secondary to daily activities …

Pathophysiology and management of hypoglycemia in diabetes

E Sanchez‐Rangel, J Deajon‐Jackson… - Annals of the New …, 2022 - Wiley Online Library
In the century since the discovery of insulin, diabetes has changed from an early death
sentence to a manageable chronic disease. This change in longevity and duration of …

Association of hypoglycaemia with the risks of arrhythmia and mortality in individuals with diabetes-a systematic review and meta-analysis

G Li, S Zhong, X Wang, F Zhuge - Frontiers in Endocrinology, 2023 - frontiersin.org
Background Hypoglycaemia has been linked to an increased risk of cardiac arrhythmias by
causing autonomic and metabolic alterations, which may be associated with detrimental …