Extracellular vesicle nanoarchitectonics for novel drug delivery applications

S Sharma, MK Masud, YV Kaneti, P Rewatkar… - Small, 2021 - Wiley Online Library
Extracellular vesicles (EVs) can transfer intercellular messages in various (patho)
physiological processes and transport biomolecules to recipient cells. EVs possess the …

Exosomes as messengers between mother and fetus in pregnancy

L Czernek, M Düchler - International Journal of Molecular Sciences, 2020 - mdpi.com
The ability of exosomes to transport different molecular cargoes and their ability to influence
various physiological factors is already well known. An exciting area of research explores …

Mechanisms of endothelial dysfunction in pre-eclampsia and gestational diabetes mellitus: windows into future cardiometabolic health?

CJ McElwain, E Tuboly, FP McCarthy… - Frontiers in …, 2020 - frontiersin.org
Placental insufficiency and adipose tissue dysregulation are postulated to play key roles in
the pathophysiology of both pre-eclampsia (PE) and gestational diabetes mellitus (GDM). A …

Extracellular vesicles-crucial players in human pregnancy

N Paul, Z Sultana, JJ Fisher, K Maiti, R Smith - Placenta, 2023 - Elsevier
Extracellular vesicles (EVs) are lipid-bilayer enclosed membrane vesicles released by cells
in physiological and pathological states. EVs are generated and released through a variety …

Extracellular vesicles and immune response during pregnancy: A balancing act

AE Morelli, Y Sadovsky - Immunological reviews, 2022 - Wiley Online Library
The mechanisms underlying maternal tolerance of the semi‐or fully‐allogeneic fetus are
intensely investigated. Across gestation, feto‐placental antigens interact with the maternal …

The role of extracellular vesicles as allies of HIV, HCV and SARS viruses

F Giannessi, A Aiello, F Franchi, ZA Percario, E Affabris - Viruses, 2020 - mdpi.com
Extracellular vesicles (EVs) are lipid bilayer-enclosed entities containing proteins and
nucleic acids that mediate intercellular communication, in both physiological and …

Omics insights into extracellular vesicles in embryo implantation and their therapeutic utility

QH Poh, A Rai, LA Salamonsen, DW Greening - Proteomics, 2023 - Wiley Online Library
Implantation success relies on intricate interplay between the develo** embryo and the
maternal endometrium. Extracellular vesicles (EVs) represent an important player of this …

Integrins mediate placental extracellular vesicle trafficking to lung and liver in vivo

SL Nguyen, SH Ahn, JW Greenberg, BW Collaer… - Scientific Reports, 2021 - nature.com
Membrane-bound extracellular vesicles (EVs) mediate intercellular communication in all
organisms, and those produced by placental mammals have become increasingly …

Raman Spectroscopy characterization extracellular vesicles from bovine placenta and peripheral blood mononuclear cells

H Zhang, AC Silva, W Zhang, H Rutigliano, A Zhou - PloS one, 2020 - journals.plos.org
Placenta-derived extracellular vesicles (EVs) are involved in communication between the
placenta and maternal immune cells possibly leading to a modulation of maternal T-cell …

Pulmonary silicosis alters microRNA expression in rat lung and miR-411-3p exerts anti-fibrotic effects by inhibiting MRTF-A/SRF signaling

X Gao, D Xu, S Li, Z Wei, S Li, W Cai, N Mao… - … Therapy-Nucleic Acids, 2020 - cell.com
To identify potential therapeutic targets for pulmonary fibrosis induced by silica, we studied
the effects of this disease on the expression of microRNAs (miRNAs) in the lung. Rattus …