Mechanisms of antiviral immune evasion of SARS-CoV-2

DK Beyer, A Forero - Journal of molecular biology, 2022 - Elsevier
Abstract Coronavirus disease (COVID-19) is caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) and is characterized by a delayed interferon (IFN) response …

Correlated evolution of social organization and lifespan in mammals

P Zhu, W Liu, X Zhang, M Li, G Liu, Y Yu, Z Li… - Nature …, 2023 - nature.com
Discerning the relationship between sociality and longevity would permit a deeper
understanding of how animal life history evolved. Here, we perform a phylogenetic …

The role of SRP9/SRP14 in regulating Alu RNA

D Gussakovsky, NA Black, EP Booy, SA McKenna - RNA biology, 2024 - Taylor & Francis
ABSTRACT SRP9/SRP14 is a protein heterodimer that plays a critical role in the signal
recognition particle through its interaction with the scaffolding signal recognition particle …

Exploring unconventional attributes of red blood cells and their potential applications in biomedicine

AT Anastasiadi, VZ Arvaniti, KE Hudson… - Protein & …, 2024 - academic.oup.com
Eukaryotic cells are defined as cells containing distinct nuclei and other membranous
organelles. However, red blood cells (RBCs) lack a nucleus and organelles—perhaps to …

High-Temperature Stress Effect on the Red Cusk-Eel (Geypterus chilensis) Liver: Transcriptional Modulation and Oxidative Stress Damage

P Dettleff, R Zuloaga, M Fuentes, P Gonzalez, J Aedo… - Biology, 2022 - mdpi.com
Simple Summary The red cusk-eel (Genypterus chilensis) is a native Chilean species
important for aquaculture diversification in Chile. The effect of high-temperature stress on the …

In Vivo Investigation of the Effect of Dietary Acrylamide and Evaluation of Its Clinical Relevance in Colon Cancer

CM Neophytou, A Katsonouri, MI Christodoulou… - Toxics, 2023 - mdpi.com
Dietary exposure to acrylamide (AA) has been linked with carcinogenicity in the
gastrointestinal (GI) tract. However, epidemiologic data on AA intake in relation to cancer …

Host cells actively resist porcine reproductive and respiratory syndrome virus infection via the IRF8-microRNA-10a-SRP14 regulatory pathway

Z Zheng, X Fu, X Ling, H Sun, Y Li, Z Ma, B Wei… - Journal of …, 2022 - Am Soc Microbiol
MicroRNAs (miRNAs) play an important role in the virus-host interaction. Our previous work
has indicated that the expression level of miR-10a increased in porcine alveolar …

The pro-oncogenic sphingolipid-metabolizing enzyme β-galactosylceramidase modulates the proteomic landscape in BRAF (V600E)-mutated human melanoma cells

D Capoferri, P Chiodelli, M Corli, M Belleri… - International Journal of …, 2023 - mdpi.com
β-Galactosylceramidase (GALC) is a lysosomal enzyme involved in sphingolipid metabolism
by removing β-galactosyl moieties from β-galactosylceramide and β-galactosylsphingosine …

Germline Predisposition to Hematopoietic Malignancies: An Overview

Y Haribabu, E Bhote, LA Godley - Annual Review of Cancer …, 2024 - annualreviews.org
Deleterious germline variants are now recognized as common drivers of hematopoietic
malignancies (HMs) and bone marrow failure syndromes. With the increasing use of …

Comparative transcriptomic insights into molecular mechanisms of the susceptibility wheat variety MX169 response to Puccinia striiformis f. sp. tritici (Pst) infection

X Lv, J Deng, C Zhou, A Abdullah, Z Yang… - Microbiology …, 2024 - journals.asm.org
Stripe rust of wheat is caused by the fungal pathogen Puccinia striiformis f. sp. tritici (Pst).
Breeding durably resistant wheat varieties by disrupting the susceptibility (S) gene has an …