Cytolytic peptide and protein toxins from sea anemones (Anthozoa: Actiniaria)
More than 32 species of sea anemones have been reported to produce lethal cytolytic
peptides and proteins. Based on their primary structure and functional properties, cytolysins …
peptides and proteins. Based on their primary structure and functional properties, cytolysins …
[HTML][HTML] Pore formation by actinoporins, cytolysins from sea anemones
Actinoporins (APs) from sea anemones are~ 20 kDa pore forming toxins with a β-sandwich
structure flanked by two α-helices. The molecular mechanism of APs pore formation is …
structure flanked by two α-helices. The molecular mechanism of APs pore formation is …
Crystal and electron microscopy structures of sticholysin II actinoporin reveal insights into the mechanism of membrane pore formation
Sticholysin II (StnII) is a pore-forming protein (PFP) produced by the sea anemone
Stichodactyla helianthus. We found out that StnII exists in a monomeric soluble state but …
Stichodactyla helianthus. We found out that StnII exists in a monomeric soluble state but …
Crystal structure of the soluble form of equinatoxin II, a pore-forming toxin from the sea anemone Actinia equina
Background: Membrane pore–forming toxins have a remarkable property: they adopt a
stable soluble form structure, which, when in contact with a membrane, undergoes a series …
stable soluble form structure, which, when in contact with a membrane, undergoes a series …
Two-step membrane binding by Equinatoxin II, a pore-forming toxin from the sea anemone, involves an exposed aromatic cluster and a flexible helix
Equinatoxin II (EqtII) belongs to a unique family of 20-kDa pore-forming toxins from sea
anemones. These toxins preferentially bind to membranes containing sphingomyelin and …
anemones. These toxins preferentially bind to membranes containing sphingomyelin and …
[HTML][HTML] Effects of lipid composition on membrane permeabilization by sticholysin I and II, two cytolysins of the sea anemone Stichodactyla helianthus
Abstract Sticholysin I and II (St I and St II), two basic cytolysins purified from the Caribbean
sea anemone Stichodactyla helianthus, efficiently permeabilize lipid vesicles by forming …
sea anemone Stichodactyla helianthus, efficiently permeabilize lipid vesicles by forming …
Molecular determinants of sphingomyelin specificity of a eukaryotic pore-forming toxin
B Bakrac, I Gutiérrez-Aguirre, Z Podlesek… - Journal of Biological …, 2008 - ASBMB
Sphingomyelin (SM) is abundant in the outer leaflet of the cell plasma membrane, with the
ability to concentrate in so-called lipid rafts. These specialized cholesterol-rich …
ability to concentrate in so-called lipid rafts. These specialized cholesterol-rich …
Transmembrane protein topology map** by the substituted cysteine accessibility method (SCAMTM): application to lipid-specific membrane protein topogenesis
We provide an overview of lipid-dependent polytopic membrane protein topogenesis, with
particular emphasis on Escherichia coli strains genetically altered in their lipid composition …
particular emphasis on Escherichia coli strains genetically altered in their lipid composition …
[HTML][HTML] Sticholysins, two pore-forming toxins produced by the Caribbean Sea anemone Stichodactyla helianthus: their interaction with membranes
Sticholysins (Sts) I and II (StI/II) are pore-forming toxins (PFTs) produced by the Caribbean
Sea anemone Stichodactyla helianthus belonging to the actinoporin family, a unique class …
Sea anemone Stichodactyla helianthus belonging to the actinoporin family, a unique class …
Solution structure of the eukaryotic pore-forming cytolysin equinatoxin II: implications for pore formation
Sea anemones produce a family of 18–20 kDa proteins, the actinoporins, that lyse cells by
forming pores in cell membranes. Sphingomyelin plays an important role in their lytic activity …
forming pores in cell membranes. Sphingomyelin plays an important role in their lytic activity …