Management of hyperglycemia in type 2 diabetes: a patient-centered approach: position statement of the American Diabetes Association (ADA) and the European …

SE Inzucchi, RM Bergenstal, JB Buse… - Diabetes …, 2012‏ - Am Diabetes Assoc
Moderate aLimited use in the US/Europe. bNot licensed in the US cPrescribing highly
restricted in the US; withdrawn in Europe. dNot licensed in Europe. eTo be available as a …

Metabolic syndrome and insulin resistance: perioperative considerations.

HS Bagry, S Raghavendran, F Carli - Anesthesiology, 2008‏ - europepmc.org
Metabolic syndrome represents a constellation of risk factors associated with increased
incidence of cardiovascular disease and progression to diabetes mellitus. Insulin resistance …

Management of hyperglycaemia in type 2 diabetes: a patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European …

SE Inzucchi, RM Bergenstal, JB Buse, M Diamant… - Diabetologia, 2012‏ - Springer
Glycaemic management in type 2 diabetes mellitus has become increasingly complex and,
to some extent, controversial, with a widening array of pharmacological agents now …

Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes

SE Nissen, K Wolski - New England Journal of Medicine, 2007‏ - Mass Medical Soc
Background Rosiglitazone is widely used to treat patients with type 2 diabetes mellitus, but
its effect on cardiovascular morbidity and mortality has not been determined. Methods We …

Effects of metformin versus glipizide on cardiovascular outcomes in patients with type 2 diabetes and coronary artery disease

J Hong, Y Zhang, S Lai, A Lv, Q Su, Y Dong… - Diabetes …, 2013‏ - Am Diabetes Assoc
OBJECTIVE The two major classes of antidiabetic drugs, sulfonylureas and metformin, may
differentially affect macrovascular complications and mortality in diabetic patients. We …

Does hypoglycaemia increase the risk of cardiovascular events? A report from the ORIGIN trial

ORIGIN Trial Investigators Mellbin Linda G … - European heart …, 2013‏ - academic.oup.com
Aims Hypoglycaemia caused by glucose-lowering therapy has been linked to
cardiovascular (CV) events. The ORIGIN trial provides an opportunity to further assess this …

Effect of muraglitazar on death and major adverse cardiovascular events in patients with type 2 diabetes mellitus

SE Nissen, K Wolski, EJ Topol - Jama, 2005‏ - jamanetwork.com
ContextPeroxisome proliferator–activated receptors (PPARs) are nuclear transcription
factors that modulate gene expression. Therapeutic agents targeting 2 distinct families of …

Dose–response relation between sulfonylurea drugs and mortality in type 2 diabetes mellitus: a population-based cohort study

SH Simpson, SR Majumdar, RT Tsuyuki, DT Eurich… - Cmaj, 2006‏ - Can Med Assoc
Background: Over the past 30 years, the relation between use of sulfonylureas to treat type 2
diabetes and the risk of cardiovascular events has been vigorously debated. The purpose of …

The impact of glucose lowering treatment on long-term prognosis in patients with type 2 diabetes and myocardial infarction: a report from the DIGAMI 2 trial

LG Mellbin, K Malmberg, A Norhammar… - European heart …, 2008‏ - academic.oup.com
Aims To explore the impact of glucose lowering treatment on prognosis in diabetic patients
with myocardial infarction. Methods and results 1181 type 2 diabetic patients (mean age 68 …

Pharmacologic differences of sulfonylureas and the risk of adverse cardiovascular and hypoglycemic events

A Douros, H Yin, OHY Yu, KB Filion, L Azoulay… - Diabetes …, 2017‏ - Am Diabetes Assoc
OBJECTIVE Sulfonylureas have been associated with an increased risk of cardiovascular
adverse events and hypoglycemia, but it is unclear if these risks vary with different agents …