Pre-eclampsia
Pre-eclampsia is a multisystem pregnancy disorder characterised by variable degrees of
placental malperfusion, with release of soluble factors into the circulation. These factors …
placental malperfusion, with release of soluble factors into the circulation. These factors …
Preeclampsia: pathophysiology, challenges, and perspectives
Hypertensive disorders of pregnancy—chronic hypertension, gestational hypertension, and
preeclampsia—are uniquely challenging as the pathology and its therapeutic management …
preeclampsia—are uniquely challenging as the pathology and its therapeutic management …
The 2021 International Society for the Study of Hypertension in Pregnancy classification, diagnosis & management recommendations for international practice
All units managing hypertensive pregnant women should maintain and review uniform
departmental management protocols and conduct regular audits of maternal & fetal …
departmental management protocols and conduct regular audits of maternal & fetal …
Pre-eclampsia: pathogenesis, novel diagnostics and therapies
EA Phipps, R Thadhani, T Benzing… - Nature Reviews …, 2019 - nature.com
Pre-eclampsia is a complication of pregnancy that is associated with substantial maternal
and fetal morbidity and mortality. The disease presents with new-onset hypertension and …
and fetal morbidity and mortality. The disease presents with new-onset hypertension and …
Hypertensive disorders of pregnancy: ISSHP classification, diagnosis, and management recommendations for international practice
4. There are significant long-term cardiovascular risks for women with chronic hypertension
and those who have had gestational hypertension or preeclampsia. One initial …
and those who have had gestational hypertension or preeclampsia. One initial …
Tracking placental development in health and disease
Pre-eclampsia and fetal growth restriction arise from disorders of placental development and
have some shared mechanistic features. Initiation is often rooted in the maldevelopment of a …
have some shared mechanistic features. Initiation is often rooted in the maldevelopment of a …
[HTML][HTML] Imbalances in circulating angiogenic factors in the pathophysiology of preeclampsia and related disorders
Preeclampsia is a devastating medical complication of pregnancy that can lead to significant
maternal and fetal morbidity and mortality. It is currently believed that there is abnormal …
maternal and fetal morbidity and mortality. It is currently believed that there is abnormal …
Predictive value of the sFlt-1: PlGF ratio in women with suspected preeclampsia
H Zeisler, E Llurba, F Chantraine… - … England Journal of …, 2016 - Mass Medical Soc
Background The ratio of soluble fms-like tyrosine kinase 1 (sFlt-1) to placental growth factor
(PlGF) is elevated in pregnant women before the clinical onset of preeclampsia, but its …
(PlGF) is elevated in pregnant women before the clinical onset of preeclampsia, but its …
Pre-eclampsia
Summary Pre-eclampsia affects 3–5% of pregnancies and is traditionally diagnosed by the
combined presentation of high blood pressure and proteinuria. New definitions also include …
combined presentation of high blood pressure and proteinuria. New definitions also include …
The classification, diagnosis and management of the hypertensive disorders of pregnancy: a revised statement from the ISSHP
There has never been a definite consensus on the classification and diagnostic criteria for
the hypertensive disorders of pregnancy. This uncertainty is likely to have led to between …
the hypertensive disorders of pregnancy. This uncertainty is likely to have led to between …