Alzheimer's disease (AD) is the most common form of dementia worldwide. β-amyloid
peptide (Aβ) is currently assumed to be the main cause of synaptic dysfunction and cognitive …

The goal of this review is to discuss how behavioral tests in mice relate to the pathological
and neuropsychological features seen in human Alzheimer's disease (AD), and present a …

The neurotransmitter acetylcholine (ACh) can regulate neuronal excitability by acting on the
cys-loop cation-conducting ligand-gated nicotinic ACh receptor (nAChR) channels. These …

Converging lines of evidence suggest that progressive accumulation of the amyloid β‐
protein (Aβ) plays a central role in the genesis of Alzheimer's disease, but it was long …

Alzheimer's disease, the most prevalent form of dementia in the elderly, is characterized by
progressive memory loss and cognitive dysfunction. It has become increasingly clear that …

Neuronal nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels that are
widely distributed both pre-and post-synaptically in the mammalian brain. By modulating …

Recent evidence implicates exosomes in the aggregation of Aβ and spreading of tau in
Alzheimer9s disease. In neural cells, exosome formation can be blocked by inhibition or …

Alzheimer's disease (AD) is the most common cause of dementia, affecting 35 million people
today. The search for new treatments is made ever more urgent by prospects for increasing …

Synapse loss is an early and invariant feature of Alzheimer's disease (AD) and there is a
strong correlation between the extent of synapse loss and the severity of dementia …

Learning and memory depend on dendritic spine actin assembly and docosahexaenoic acid
(DHA), an essential n-3 (omega-3) polyunsaturated fatty acid (PFA). High DHA consumption …