[HTML][HTML] The therapeutic use of quercetin in ophthalmology: Recent applications

L Zhao, H Wang, X Du - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Quercetin is a natural flavonol antioxidant found in various plant sources and food samples.
It is well known for its notable curative effects on the treatment of ophthalmic diseases due to …

Space radiation protection countermeasures in microgravity and planetary exploration

CA Montesinos, R Khalid, O Cristea, JS Greenberger… - Life, 2021 - mdpi.com
Background: Space radiation is one of the principal environmental factors limiting the human
tolerance for space travel, and therefore a primary risk in need of mitigation strategies to …

Quercetin inhibits the production of IL-1β-induced inflammatory cytokines and chemokines in ARPE-19 cells via the MAPK and NF-κB signaling pathways

SC Cheng, WC Huang, JH S. Pang, YH Wu… - International journal of …, 2019 - mdpi.com
Quercetin, a bioflavonoid derived from vegetables and fruits, exerts anti-inflammatory effects
in various diseases. Our previous study revealed that quercetin could suppress the …

[HTML][HTML] Potential benefits of Malva sylvestris in dry-eye disease pathology in vitro based on antioxidant, wound-healing and anti-inflammatory properties

A Areesanan, S Nicolay, M Keller… - Biomedicine & …, 2023 - Elsevier
Dry eye disease (DED) is a common chronic ocular surface disease. Available therapies are
effective but often associated with side effects. This study investigates the potential of a …

The biological and pharmacological roles of polyphenol flavonoid tilianin

MR Akanda, MN Uddin, IS Kim, D Ahn, HJ Tae… - European Journal of …, 2019 - Elsevier
Archaeological evidence for phytomedicine has established the importance of plants as a
source of biologically active molecules with beneficial effects. Related studies constitute …

Quercetin inhibits LPS-induced inflammation and ox-LDL-induced lipid deposition

F Xue, X Nie, J Shi, Q Liu, Z Wang, X Li… - Frontiers in …, 2017 - frontiersin.org
Aberrant activation of inflammation and excess accumulation of lipids play crucial role in the
occurrence and progression of atherosclerosis (AS). Quercetin (QCT) has been tested …

Topical quercetin and resveratrol protect the ocular surface in experimental dry eye disease

A Abengózar-Vela, CS Schaumburg… - Ocular Immunology …, 2019 - Taylor & Francis
Purpose: To determine the anti-inflammatory effect of quercetin (QCT), resveratrol (RES),
and their combination in a dry eye disease (DED) model. Methods: 0.01% QCT, 0.1% RES …

[HTML][HTML] Improved ocular delivery of quercetin and resveratrol: A comparative study between binary and ternary cyclodextrin complexes

L Krstić, P Jarho, M Ruponen, A Urtti… - International Journal of …, 2022 - Elsevier
The number of patients affected by Dry Eye Disease (DED) had notably increased
worldwide, addressing the need of novel therapeutic approaches. Polyphenols, quercetin …

[HTML][HTML] The potential benefits of polyphenols for corneal diseases

J Feng, Y Zhang - Biomedicine & Pharmacotherapy, 2023 - Elsevier
The cornea functions as the primary barrier of the ocular surface, regulating temperature and
humidity while providing protection against oxidative stress, harmful stimuli and pathogenic …

Olive pomace phenolic compounds and extracts can inhibit inflammatory-and oxidative-related diseases of human ocular surface epithelium

N Katsinas, S Rodríguez-Rojo… - Antioxidants, 2021 - mdpi.com
Oxidative-and inflammatory-related ocular surface diseases have high prevalence and are
an emerging issue in ophthalmology. Olive pomace (OP) is the olive oil's industry main by …