[HTML][HTML] Metabolic control by sirtuins and other enzymes that sense NAD+, NADH, or their ratio

KA Anderson, AS Madsen, CA Olsen… - Biochimica et Biophysica …, 2017‏ - Elsevier
NAD+ is a dinucleotide cofactor with the potential to accept electrons in a variety of cellular
reduction-oxidation (redox) reactions. In its reduced form, NADH is a ubiquitous cellular …

Phosphatidic acid in membrane rearrangements

MA Zhukovsky, A Filograna, A Luini, D Corda… - Febs …, 2019‏ - Wiley Online Library
Phosphatidic acid (PA) is the simplest cellular glycerophospholipid characterized by unique
biophysical properties: a small headgroup; negative charge; and a phosphomonoester …

Sites of neocortical reorganization critical for remote spatial memory

T Maviel, TP Durkin, F Menzaghi, B Bontempi - Science, 2004‏ - science.org
The hippocampus is crucial for spatial memory formation, yet it does not store long-lasting
memories. By combining functional brain imaging and region-specific neuronal inactivation …

Mechanism of leaf-shape determination

H Tsukaya - Annu. Rev. Plant Biol., 2006‏ - annualreviews.org
Biodiversity of plant shape is mainly attributable to biodiversity of leaf shape and the shape
of floral organs, the modified leaves. However, the exact mechanisms of leaf-shape …

[PDF][PDF] Leaf shape: genetic controls and environmental factors

H Tsukaya - The International journal of developmental biology, 2005‏ - scholar.archive.org
In recent years, many genes have been identified that are involved in the developmental
processes of leaf morphogenesis. Here, I review the mechanisms of leaf shape control in a …

Differential binding of NAD+ and NADH allows the transcriptional corepressor carboxyl-terminal binding protein to serve as a metabolic sensor

CC Fjeld, WT Birdsong… - Proceedings of the …, 2003‏ - National Acad Sciences
Carboxyl-terminal binding protein (CtBP) is a transcriptional corepressor originally identified
through its ability to interact with adenovirus E1A. The finding that CtBP–E1A interactions …

Tackling undruggable targets with designer peptidomimetics and synthetic biologics

CS Swenson, G Mandava, DM Thomas… - Chemical …, 2024‏ - ACS Publications
The development of potent, specific, and pharmacologically viable chemical probes and
therapeutics is a central focus of chemical biology and therapeutic development. However, a …

Transcriptional regulation by C-terminal binding proteins

G Chinnadurai - The international journal of biochemistry & cell biology, 2007‏ - Elsevier
C-terminal binding protein family members function predominantly as transcriptional
corepressors in association with sequence specific DNA-binding transcriptional repressors …

Spatial control of cell expansion by the plant cytoskeleton

LG Smith, DG Oppenheimer - Annu. Rev. Cell Dev. Biol., 2005‏ - annualreviews.org
The cytoskeleton plays important roles in plant cell shape determination by influencing the
patterns in which cell wall materials are deposited. Cortical microtubules are thought to …

Sirtuins: molecular traffic lights in the crossroad of oxidative stress, chromatin remodeling, and transcription

R Rajendran, R Garva… - BioMed Research …, 2011‏ - Wiley Online Library
Transcription is regulated by acetylation/deacetylation reactions of histone and nonhistone
proteins mediated by enzymes called KATs and HDACs, respectively. As a major …