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Serial femtosecond crystallography
With the advent of X-ray free-electron lasers (XFELs), new, high-throughput serial
crystallography techniques for macromolecular structure determination have emerged …
crystallography techniques for macromolecular structure determination have emerged …
Using X-ray free-electron lasers for spectroscopy of molecular catalysts and metalloenzymes
The metal centres in metalloenzymes and molecular catalysts are responsible for the
rearrangement of atoms and electrons during complex chemical reactions, and they enable …
rearrangement of atoms and electrons during complex chemical reactions, and they enable …
DIALS: implementation and evaluation of a new integration package
The DIALS project is a collaboration between Diamond Light Source, Lawrence Berkeley
National Laboratory and CCP4 to develop a new software suite for the analysis of …
National Laboratory and CCP4 to develop a new software suite for the analysis of …
Structure of photosystem II and substrate binding at room temperature
Light-induced oxidation of water by photosystem II (PS II) in plants, algae and cyanobacteria
has generated most of the dioxygen in the atmosphere. PS II, a membrane-bound multi …
has generated most of the dioxygen in the atmosphere. PS II, a membrane-bound multi …
[HTML][HTML] Recent results in time resolved serial femtosecond crystallography at XFELs
Highlights•Time-resolved serial femtosecond crystallography (tr-SFX) probes structure and
function in each sample.•X-ray free electron lasers (XFELS) provide atomic and electronic …
function in each sample.•X-ray free electron lasers (XFELS) provide atomic and electronic …
X-ray free-electron lasers for the structure and dynamics of macromolecules
X-ray free-electron lasers provide femtosecond-duration pulses of hard X-rays with a peak
brightness approximately one billion times greater than is available at synchrotron radiation …
brightness approximately one billion times greater than is available at synchrotron radiation …
Viral internal ribosomal entry sites: four classes for one goal
To ensure efficient propagation, viruses need to rapidly produce viral proteins after cell
entrance. Since viral genomes do not encode any components of the protein biosynthesis …
entrance. Since viral genomes do not encode any components of the protein biosynthesis …
Double-flow focused liquid injector for efficient serial femtosecond crystallography
Serial femtosecond crystallography requires reliable and efficient delivery of fresh crystals
across the beam of an X-ray free-electron laser over the course of an experiment. We …
across the beam of an X-ray free-electron laser over the course of an experiment. We …
Strategies for sample delivery for femtosecond crystallography
Highly efficient data-collection methods are required for successful macromolecular
crystallography (MX) experiments at X-ray free-electron lasers (XFELs). XFEL beamtime is …
crystallography (MX) experiments at X-ray free-electron lasers (XFELs). XFEL beamtime is …
Structural insights into functional properties of the oxidized form of cytochrome c oxidase
Cytochrome c oxidase (C c O) is an essential enzyme in mitochondrial and bacterial
respiration. It catalyzes the four-electron reduction of molecular oxygen to water and …
respiration. It catalyzes the four-electron reduction of molecular oxygen to water and …