The reconceptualization of Alzheimer's disease (AD) as a clinical and biological construct
has facilitated the development of biomarker-guided, pathway-based targeted therapies …

Speech represents a promising novel biomarker by providing a window into brain health, as
shown by its disruption in various neurological and psychiatric diseases. As with many novel …

Biomarker testing is recommended for the accurate and timely diagnosis of Alzheimer's
disease (AD). Using illustrative case narratives we consider how cerebrospinal fluid (CSF) …

Importance The Clinical Dementia Rating (CDR) is a well-validated instrument widely used
to detect and stage dementia due to Alzheimer disease. The digital Electronic Clinical …

Mild cognitive impairment (MCI), representing the 'transitional zone'between normal
cognition and dementia, has become a novel topic in clinical research. Although early …

Integrating the brain structural and functional connectivity features is of great significance in
both exploring brain science and analyzing cognitive impairment clinically. However, it …

Introduction Mild cognitive impairment remains substantially underdiagnosed, especially in
disadvantaged populations. Failure to diagnose deprives patients and families of the …

INTRODUCTION This systematic review evaluates the accuracy of the Montreal Cognitive
Assessment (MoCA) for detecting mild cognitive impairment (MCI). METHODS We searched …

Topics discussed at the “Leveraging Existing Data and Analytic Methods for Health
Disparities Research Related to Aging and Alzheimer's Disease and Related Dementias” …

Abstract Motor and Cognitive Dual-Task (MCDT) represents an innovative chance to assess
Mild Cognitive Impairment (MCI). We compare two novel MCDTs, fore-finger tap** (FTAP) …