Biosynthesis, evolution and ecology of microbial terpenoids

M Avalos, P Garbeva, L Vader, GP van Wezel… - Natural Product …, 2022 - pubs.rsc.org
Covering: through June 2021 Terpenoids are the largest class of natural products
recognised to date. While mostly known to humans as bioactive plant metabolites and part of …

Four billion years of microbial terpenome evolution

Y Hoshino, L Villanueva - FEMS Microbiology Reviews, 2023 - academic.oup.com
Terpenoids, also known as isoprenoids, are the largest and most diverse class of organic
compounds in nature and are involved in many membrane-associated cellular processes …

Terpene biosynthesis in marine sponge animals

K Wilson, T de Rond, I Burkhardt, TS Steele… - Proceedings of the …, 2023 - pnas.org
Sea sponges are the largest marine source of small-molecule natural products described to
date. Sponge-derived molecules, such as the chemotherapeutic eribulin, the calcium …

Systematic mining of fungal chimeric terpene synthases using an efficient precursor-providing yeast chassis

R Chen, Q Jia, X Mu, B Hu, X Sun, Z Deng… - Proceedings of the …, 2021 - pnas.org
Chimeric terpene synthases, which consist of C-terminal prenyltransferase (PT) and N-
terminal class I terpene synthase (TS) domains (termed PTTSs here), is unique to fungi and …

Ancient origin and conserved gene function in terpene pheromone and defense evolution of stink bugs and hemipteran insects

Z Rebholz, J Lancaster, H Larose, A Khrimian… - Insect Biochemistry and …, 2023 - Elsevier
Insects use diverse arrays of small molecules such as metabolites of the large class of
terpenes for intra-and inter-specific communication and defense. These molecules are …

Functional characterization of a farnesyl diphosphate synthase from Dendrobium nobile Lindl

D Gong, B Wu, H Qin, D Fu, S Guo, B Wang, B Li - Amb Express, 2022 - Springer
Dendrobium nobile Lindl. has been used as a traditional Chinese medicine for a long time,
in which the most important compound is dendrobine functioning in a variety of …

Herbivory-Induced Emission of Volatile Terpenes in Chrysanthemum morifolium Functions as an Indirect Defense against Spodoptera litura Larvae by Attracting …

M Xu, Y Jiang, S Chen, F Chen… - Journal of Agricultural and …, 2021 - ACS Publications
Indirect defense is an important strategy employed by sessile plants to defend against
herbivorous insects by recruiting the natural enemies of herbivores mediated by herbivore …

Canonical terpene synthases in arthropods: Intraphylum gene transfer

X Chen, JM Urban, J Wurlitzer, X Wei, J Han… - Proceedings of the …, 2024 - pnas.org
Insects employ terpenoids for communication both within and between species. While
terpene synthases derived from isoprenyl diphosphate synthase have been shown to …

Biocompatible fluorocarbon liquid underlays for in situ extraction of isoprenoids from microbial cultures

S Overmans, KJ Lauersen - RSC advances, 2022 - pubs.rsc.org
Microbial production of heterologous metabolites is now a mature technology in many host
organisms, opening new avenues for green production processes of specialty chemicals. At …

Terpenoid Biosynthesis Dominates among Secondary Metabolite Clusters in Mucoromycotina Genomes

G Koczyk, J Pawłowska, A Muszewska - Journal of Fungi, 2021 - mdpi.com
Early-diverging fungi harbour unprecedented diversity in terms of living forms, biological
traits and genome architecture. Before the sequencing era, non-Dikarya fungi were …