A Comprehensive Analytical Review of Polyphenols: Evaluating Neuroprotection in Alzheimer's Disease

D Vicente-Zurdo, E Gómez-Mejía… - International Journal of …, 2024 - mdpi.com
Alzheimer's Disease (AD), a prevalent neurodegenerative disorder, is the primary cause of
dementia. Despite significant advancements in neuroscience, a definitive cure or treatment …

[HTML][HTML] Olive Oil Industry By-Products as a Novel Source of Biophenols with a Promising Role in Alzheimer Disease Prevention

M Gonçalves, M Costa, F Paiva-Martins, P Silva - Molecules, 2024 - mdpi.com
This review explores the potential health benefits and applications of phenolic secoiridoids
derived from olive oil by-products in the prevention of Alzheimer's disease (AD). As reviewed …

Cheese-whey permeate improves the fitness of Escherichia coli cells during recombinant protein production

M de Divitiis, D Ami, A Pessina, A Palmioli… - … for Biofuels and …, 2023 - Springer
Background Escherichia coli cells are the most frequently used hosts in recombinant protein
production processes and mainly require molecules such as IPTG or pure lactose as …

Hop leaves: From waste to a valuable source of bioactive compounds–A multidisciplinary approach to investigating potential applications

G Sabbatini, E Mari, MG Ortore, A Di Gregorio… - Heliyon, 2024 - cell.com
After harvesting of cones used for beer production, the remaining hop vegetative biomass
requires disposal. The hop plant contains bioactive compounds in all its parts—cones …

Cell-Free and In Vivo Characterization of the Inhibitory Activity of Lavado Cocoa Flavanols on the Amyloid Protein Ataxin-3: Toward New Approaches against …

B Sciandrone, A Palmioli, C Ciaramelli… - ACS Chemical …, 2023 - ACS Publications
Spinocerebellar ataxia type 3 (SCA3) is a neurodegenerative disorder characterized by
ataxia and other neurological manifestations, with a poor prognosis and a lack of effective …

Synthesis and biological evaluation of coumarin triazoles as dual inhibitors of cholinesterases and β-secretase

A Sharma, SB Bharate - ACS omega, 2023 - ACS Publications
Coumarin is a naturally occurring bioactive pharmacophore with wide occurrence among
central nervous system (CNS)-active small molecules. 8-Acetylcoumarin, one of the natural …

Enhancing amyloid beta inhibition and disintegration by natural compounds: A study utilizing spectroscopy, microscopy and cell biology

R Pariary, G Shome, T Dutta, A Roy, AK Misra… - Biophysical …, 2024 - Elsevier
Amyloid proteins and peptides play a pivotal role in the etiology of various
neurodegenerative diseases, including Alzheimer's disease (AD). Synthetically designed …

[HTML][HTML] Unlocking the in vitro neuroprotection of sloe residues phenolic extracts by bioanalytical and chemometric strategies

E Gómez-Mejía, D Vicente-Zurdo, N Rosales-Conrado… - Food Chemistry, 2025 - Elsevier
Wild fruits, particularly the underutilized sloe (Prunus spinosa), are gaining interest as
natural antioxidants, with residues from liqueur production being a source of bioactive …

[HTML][HTML] Saponins Effect on Human Insulin Amyloid Aggregation

E Mari, S Vilasi, P Moretti, MR Mangione, G Giorgini… - Biomolecules, 2024 - mdpi.com
The misfolding and amyloid aggregation of proteins have been attracting scientific interest
for a few decades, due to their link with several diseases, particularly neurodegenerative …

Moderate India Pale Ale beer consumption promotes antigenotoxic and non‐mutagenic effects in ex vivo and in vivo mice models

S de Cordova Kindermann, G Caon… - Journal of the …, 2024 - Wiley Online Library
BACKGROUND Discussion of the benefits of moderate alcohol consumption is ongoing.
Broadly, research focusing on ethanol consumption tends to report no benefits. However …