Neonatal exposure to bisphenol a alters reproductive parameters and gonadotropin releasing hormone signaling in female rats

M Fernández, M Bianchi, V Lux-Lantos… - Environmental health …, 2009 - ehp.niehs.nih.gov
Background Bisphenol A (BPA) is a component of polycarbonate plastics, epoxy resins, and
polystyrene and is found in many products. Several reports have revealed potent in vivo …

Mitogen-activated protein kinases in normal and (pre) neoplastic ovarian surface epithelium

KC Choi, N Auersperg, PCK Leung - Reproductive biology and …, 2003 - Springer
Mitogen-activated protein kinases (MAPKs) are a group of serine/threonine kinases which
are activated in response to a diverse array of extracellular stimuli and mediate signal …

Mechanism of gonadotropin-releasing hormone (GnRH)-I and-II-induced cell growth inhibition in ovarian cancer cells: role of the GnRH-I receptor and protein kinase …

KY Kim, KC Choi, N Auersperg… - Endocrine-related …, 2006 - erc.bioscientifica.com
In our previous studies, we demonstrated that ERK1/2 (extracellular signal-regulated protein
kinase) and p38 MAPK (mitogen-activated protein kinase) are required for gonadotropin …

Effects of orexins A and B on expression of orexin receptors and progesterone release in luteal and granulosa ovarian cells

NI Cataldi, VAR Lux-Lantos, C Libertun - Regulatory Peptides, 2012 - Elsevier
Orexin-A and orexin-B are neuropeptides controlling sleep-wakefulness, feeding and
neuroendocrine functions via their G protein-coupled receptors, orexin-1R and orexin-2R …

Gonadotropins regulate N-cadherin-mediated human ovarian surface epithelial cell survival at both post-translational and transcriptional levels through a cyclic AMP …

YL Pon, N Auersperg, AST Wong - Journal of Biological Chemistry, 2005 - ASBMB
Gonadotropins are the major regulators of ovarian function and may be involved in the
etiology of ovarian cancer. In this study, we report a new mechanism whereby …

Signaling events associated with gonadotropin releasing hormone‐agonist‐induced hormonal castration and its reversal in canines

A Bulldan, M Shihan, S Goericke‐Pesch… - Molecular …, 2016 - Wiley Online Library
SUMMARY A gonadotropin‐releasing hormone agonist (GnRH‐A) implant induces
hormonal castration in dogs that is associated with reduced prostate and testes size. We …

GnRH agonists: Updating fixed‐time artificial insemination protocols in sows

MV Falceto, A Suárez‐Usbeck… - … in Domestic Animals, 2023 - Wiley Online Library
Protocols for fixed‐time artificial insemination (FTAI) in swine reproduction can help increase
genetic improvement and production efficiency. Different gonadotropin‐releasing hormone …

Differential gonadotropin releasing hormone (GnRH) expression, autoregulation and effects in two models of rat luteinized ovarian cells

EM Sorianello, MO Fernandez, PN Catalano… - Life sciences, 2005 - Elsevier
GnRH has been suggested to participate in corpus luteum function. Here we studied the
expression of GnRH mRNA and peptide in two models of rat luteinized tissues: ovarian cells …

Evidence for different gonadotropin-releasing hormone response sites in rat ovarian and pituitary cells

LA Mongiat, VA Lux-Lantos, C Libertun - Biology of reproduction, 2004 - academic.oup.com
The participation of type I GnRH receptor (GnRH-R) on GnRH-II-induced gonadotropin
secretion in rat pituitary cells was investigated. Furthermore, we extended the study of GnRH …

Analysis of GnRH receptor gene expression in lines of swine with divergent ovulation rates

JE Smith - 2008 - digitalcommons.unl.edu
To examine the relationship between the molecular mechanisms underlying ovulation rate
and transcriptional regulation of the porcine GnRHR gene, our laboratory has isolated the …