miRNAs as biomarkers in disease: latest findings regarding their role in diagnosis and prognosis
CE Condrat, DC Thompson, MG Barbu, OL Bugnar… - Cells, 2020 - mdpi.com
MicroRNAs (miRNAs) represent a class of small, non-coding RNAs with the main roles of
regulating mRNA through its degradation and adjusting protein levels. In recent years …
regulating mRNA through its degradation and adjusting protein levels. In recent years …
Characterizing extracellular vesicles and their diverse RNA contents
Cells release nanometer-scale, lipid bilayer-enclosed biomolecular packages (extracellular
vesicles; EVs) into their surrounding environment. EVs are hypothesized to be intercellular …
vesicles; EVs) into their surrounding environment. EVs are hypothesized to be intercellular …
[HTML][HTML] Translating RNA sequencing into clinical diagnostics: opportunities and challenges
SA Byron, KR Van Keuren-Jensen… - Nature Reviews …, 2016 - nature.com
With the emergence of RNA sequencing (RNA-seq) technologies, RNA-based biomolecules
hold expanded promise for their diagnostic, prognostic and therapeutic applicability in …
hold expanded promise for their diagnostic, prognostic and therapeutic applicability in …
Cross-kingdom inhibition of breast cancer growth by plant miR159
MicroRNAs (miRNAs) are critical regulators of gene expression, and exert extensive impacts
on development, physiology, and disease of eukaryotes. A high degree of parallelism is …
on development, physiology, and disease of eukaryotes. A high degree of parallelism is …
[HTML][HTML] MicroRNAs are absorbed in biologically meaningful amounts from nutritionally relevant doses of cow milk and affect gene expression in peripheral blood …
Background: MicroRNAs (miRNAs) regulate genes in animals and plants and can be
synthesized endogenously. In milk, miRNAs are encapsulated in exosomes, thereby …
synthesized endogenously. In milk, miRNAs are encapsulated in exosomes, thereby …
[HTML][HTML] The intestinal transport of bovine milk exosomes is mediated by endocytosis in human colon carcinoma Caco-2 cells and rat small intestinal IEC-6 cells
T Wolf, SR Baier, J Zempleni - The Journal of nutrition, 2015 - Elsevier
Background: MicroRNAs play essential roles in gene regulation. A substantial fraction of
microRNAs in tissues and body fluids is encapsulated in exosomes, thereby conferring …
microRNAs in tissues and body fluids is encapsulated in exosomes, thereby conferring …
Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity
In mammalian systems RNA can move between cells via vesicles. Here we demonstrate that
the gastrointestinal nematode Heligmosomoides polygyrus, which infects mice, secretes …
the gastrointestinal nematode Heligmosomoides polygyrus, which infects mice, secretes …
Involvement of gut microbiome in human health and disease: brief overview, knowledge gaps and research opportunities
D Liang, RKK Leung, W Guan, WW Au - Gut pathogens, 2018 - Springer
The commensal, symbiotic, and pathogenic microbial community which resides inside our
body and on our skin (the human microbiome) can perturb host energy metabolism and …
body and on our skin (the human microbiome) can perturb host energy metabolism and …
[HTML][HTML] Biological activities of extracellular vesicles and their cargos from bovine and human milk in humans and implications for infants
Extracellular vesicles (EVs) in milk harbor a variety of compounds, including lipids, proteins,
noncoding RNAs, and mRNAs. Among the various classes of EVs, exosomes are of …
noncoding RNAs, and mRNAs. Among the various classes of EVs, exosomes are of …
Extracellular vesicle RNA: a universal mediator of microbial communication?
Both extracellular RNAs and extracellular vesicles (EVs) have recently garnered attention as
novel mediators of intercellular communication in eukaryotes and prokaryotes alike. EVs not …
novel mediators of intercellular communication in eukaryotes and prokaryotes alike. EVs not …