Microglia, the resident immune cells in the brain, are essential for modulating neurogenesis,
influencing synaptic remodeling, and regulating neuroinflammation by surveying the brain …

During the past decade, an abundance of new evidence highlighted the importance of
inflammation in the development of chronic pathologies such as neurodegeneration, cancer …

Oligodendrocyte precursor cells (OPCs) account for 5% of the resident parenchymal central
nervous system glial cells. OPCs are not only a back-up for the loss of oligodendrocytes that …

Hikikomori, a severe form of social withdrawal, has long been observed in Japan mainly
among youth and adolescents since around the 1970s, and has been especially highlighted …

Abstract Attention Deficit Hyperactivity Disorder (ADHD) is a persistent, and impairing
pediatric-onset neurodevelopmental condition. Its high prevalence, and recurrent …

Cognitive impairment in schizophrenia represents one of the main obstacles to clinical and
functional recovery. This expert group paper brings together experts in schizophrenia …

The recent outbreak of the corona virus disease (COVID-19) has had major global impact.
The relationship between severe acute respiratory syndrome coronavirus (SARS-CoV-2) …

Although the precise pathogenesis of schizophrenia is unknown, genetic, biomarker and
imaging studies suggest involvement of the immune system. In this study, we performed a …

Evidence from clinical, preclinical, and post-mortem studies supports the
inflammatory/immune hypothesis of schizophrenia pathogenesis. Less evident is the link …

Cognitive dysfunction is a well-established feature of schizophrenia, and there is evidence
suggesting that cognitive deficits are secondary to abnormal neurodevelopment leading to …