[HTML][HTML] Antiviral activities of flavonoids

SL Badshah, S Faisal, A Muhammad… - Biomedicine & …, 2021 - Elsevier
Flavonoids are natural phytochemicals known for their antiviral activity. The flavonoids acts
at different stages of viral infection, such as viral entrance, replication and translation of …

Flavonols as potential antiviral drugs targeting SARS-CoV-2 proteases (3CLpro and PLpro), spike protein, RNA-dependent RNA polymerase (RdRp) and angiotensin …

C Mouffouk, S Mouffouk, S Mouffouk… - European journal of …, 2021 - Elsevier
The novel coronavirus outbreak (COVID-19) caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) represents the actual greatest global public health crisis. The …

Role of silymarin in cancer treatment: facts, hypotheses, and questions

T Koltai, L Fliegel - Journal of Evidence-Based Integrative …, 2022 - journals.sagepub.com
The flavonoid silymarin extracted from the seeds of Sylibum marianum is a mixture of 6
flavolignan isomers. The 3 more important isomers are silybin (or silibinin), silydianin, and …

Mechanistic insights into the pharmacological significance of silymarin

K Wadhwa, R Pahwa, M Kumar, S Kumar, PC Sharma… - Molecules, 2022 - mdpi.com
Medicinal plants are considered the reservoir of diverse therapeutic agents and have been
traditionally employed worldwide to heal various ailments for several decades. Silymarin is a …

Flavonoids as promising antiviral agents against SARS-CoV-2 infection: a mechanistic review

MA Khazeei Tabari, A Iranpanah, R Bahramsoltani… - Molecules, 2021 - mdpi.com
A newly diagnosed coronavirus in 2019 (COVID-19) has affected all human activities since
its discovery. Flavonoids commonly found in the human diet have attracted a lot of attention …

Identification of alkaloids from Justicia adhatoda as potent SARS CoV-2 main protease inhibitors: An in silico perspective

R Ghosh, A Chakraborty, A Biswas… - Journal of molecular …, 2021 - Elsevier
The COVID-19 pandemic, caused by SARS CoV-2, is responsible for millions of death
worldwide. No approved/proper therapeutics is currently available which can effectively …

Flavonoids as potential phytotherapeutics to combat cytokine storm in SARS‐CoV‐2

A Gour, D Manhas, S Bag, B Gorain… - Phytotherapy …, 2021 - Wiley Online Library
Emergence of severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) infection,
COVID‐19, has become the global panic since December 2019, which urges the global …

Computer aided identification of potential SARS CoV-2 main protease inhibitors from diterpenoids and biflavonoids of Torreya nucifera leaves

R Ghosh, A Chakraborty, A Biswas… - Journal of Biomolecular …, 2022 - Taylor & Francis
SARS CoV-2 is the causative agent of the pandemic disease COVID-19. There is an urgent
need for effective drugs or vaccines which can effectively combat this outbreak. The main …

Identification of a novel inhibitor of SARS-CoV-2 3CL-PRO through virtual screening and molecular dynamics simulation

AK Bepari, HM Reza - PeerJ, 2021 - peerj.com
Background The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has ravaged lives
across the globe since December 2019, and new cases are still on the rise. Peoples' …

[HTML][HTML] Biochanin A as a modulator of the inflammatory response: an updated overview and therapeutic potential

FB Felix, JP Vago, VA Beltrami, JMD Araujo… - Pharmacological …, 2022 - Elsevier
Uncontrolled inflammation and failure to resolve the inflammatory response are crucial
factors involved in the progress of inflammatory diseases. Current therapeutic strategies …