Recombination is typically thought of as a symmetrical process resulting in large-scale
reciprocal genetic exchanges between homologous chromosomes. Recombination events …

Ciliated protozoa undergo large-scale developmental rearrangement of their somatic
genomes when forming a new transcriptionally active macronucleus during conjugation …

The macronuclear genome of the ciliate Oxytricha trifallax displays an extreme and unique
eukaryotic genome architecture with extensive genomic variation. During sexual genome …

Programmed DNA rearrangements in the single-celled eukaryote Oxytricha trifallax
completely rewire its germline into a somatic nucleus during development. This elaborate …

The germline genome of the binucleated ciliate Tetrahymena thermophila undergoes
programmed chromosome breakage and massive DNA elimination to generate the somatic …

GC-biased gene conversion (gBGC) is a process that tends to increase the GC content of
recombining DNA over evolutionary time and is thought to explain the evolution of GC …

In general, the strict preservation of broad-scale structure is thought to be critical for
maintaining the precisely tuned functionality of vertebrate genomes, although nearly all …

Background Most eukaryotic genes are subject to alternative splicing (AS), which may
contribute to the production of protein variants or to the regulation of gene expression via …

The Paramecium aurelia complex is a group of 15 species that share at least three past
whole-genome duplications (WGDs). The macronuclear genome sequences of P. biaurelia …

Insertions of parasitic DNA within coding sequences are usually deleterious and are
generally counter-selected during evolution. Thanks to nuclear dimorphism, ciliates provide …