pH-sensitive nano-systems for drug delivery in cancer therapy
Nanotechnology has been widely used in the development of new strategies for drug
delivery and cancer therapy. Compared to traditional drug delivery systems, nano-based …
delivery and cancer therapy. Compared to traditional drug delivery systems, nano-based …
Pharmacokinetics and biodistribution of nanoparticles
Nanoparticles show their promise for improving the efficacy of drugs with a narrow
therapeutic window or low bioavailability, such as anticancer drugs and nucleic acid-based …
therapeutic window or low bioavailability, such as anticancer drugs and nucleic acid-based …
Block copolymer micelles: preparation, characterization and application in drug delivery
G Gaucher, MH Dufresne, VP Sant, N Kang… - Journal of controlled …, 2005 - Elsevier
Block copolymer micelles are generally formed by the self-assembly of either amphiphilic or
oppositely charged copolymers in aqueous medium. The hydrophilic and hydrophobic …
oppositely charged copolymers in aqueous medium. The hydrophilic and hydrophobic …
pH-sensitive biomaterials for drug delivery
The development of precise and personalized medicine requires novel formulation
strategies to deliver the therapeutic payloads to the pathological tissues, producing …
strategies to deliver the therapeutic payloads to the pathological tissues, producing …
Cross-linked block copolymer micelles: functional nanostructures of great potential and versatility
Supramolecular self assembly techniques have provided a versatile means by which to
selectively assemble polymer molecules into well-defined three dimensional core–shell …
selectively assemble polymer molecules into well-defined three dimensional core–shell …
Smart chemistry-based nanosized drug delivery systems for systemic applications: a comprehensive review
This review focuses on the smart chemistry that has been utilized in develo** polymer-
based drug delivery systems over the past 10 years. We provide a comprehensive overview …
based drug delivery systems over the past 10 years. We provide a comprehensive overview …
Toward 'smart'nano-objects by self-assembly of block copolymers in solution
In recent years, the synthesis and analysis of novel copolymer-based nanomaterials in
solution have been extensively pursued. The interest in such structures lies in the fact that …
solution have been extensively pursued. The interest in such structures lies in the fact that …
Design and development of polymeric micelles with cleavable links for intracellular drug delivery
H Wei, RX Zhuo, XZ Zhang - Progress in polymer Science, 2013 - Elsevier
Driven by the urgent need in practical applications of stimuli-responsive nano-carriers for
intracellular drug delivery, the design and development of advanced polymeric micelles …
intracellular drug delivery, the design and development of advanced polymeric micelles …
pH-sensitive vesicles, polymeric micelles, and nanospheres prepared with polycarboxylates
Titratable polyanions, and more particularly polymers bearing carboxylate groups, have
been used in recent years to produce a variety of pH-sensitive colloids. These polymers …
been used in recent years to produce a variety of pH-sensitive colloids. These polymers …
Mechanisms of drug release in pH-sensitive micelles for tumour targeted drug delivery system: A review
Z Wang, X Deng, J Ding, W Zhou, X Zheng… - International journal of …, 2018 - Elsevier
During the past decades, chemotherapy has been regarded as the most effective method for
tumor therapy, but still faces significant challenges, such as poor tumor selectivity and …
tumor therapy, but still faces significant challenges, such as poor tumor selectivity and …