The regulation of endocrine-disrupting chemicals to minimize their impact on health
Endocrine-disrupting chemicals (EDCs) are substances generated by human industrial
activities that are detrimental to human health through their effects on the endocrine system …
activities that are detrimental to human health through their effects on the endocrine system …
Health risk of human exposure to microplastics: a review
KHD Tang, R Li, Z Li, D Wang - Environmental Chemistry Letters, 2024 - Springer
Microplastics are emerging contaminants that have been detected recently in most
environmental and biological systems, yet their health risk for humans has not been clearly …
environmental and biological systems, yet their health risk for humans has not been clearly …
[HTML][HTML] Developmental toxicity of Nafion byproduct 2 (NBP2) in the Sprague-Dawley rat with comparisons to hexafluoropropylene oxide-dimer acid (HFPO-DA or …
JM Conley, CS Lambright, N Evans… - Environment …, 2022 - Elsevier
Abstract Nafion byproduct 2 (NBP2) is a polyfluoroalkyl ether sulfonic acid that was recently
detected in surface water, drinking water, and human serum samples from monitoring …
detected in surface water, drinking water, and human serum samples from monitoring …
[HTML][HTML] Cumulative maternal and neonatal effects of combined exposure to a mixture of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS) …
JM Conley, CS Lambright, N Evans… - Environment …, 2022 - Elsevier
Globally, biomonitoring data demonstrate virtually all humans carry residues of multiple per-
and polyfluoroalkyl substances (PFAS). Despite pervasive co-exposure, limited mixtures …
and polyfluoroalkyl substances (PFAS). Despite pervasive co-exposure, limited mixtures …
[HTML][HTML] Cumulative risk assessment of five phthalates in European children and adolescents
R Lange, N Vogel, P Schmidt, A Gerofke… - International Journal of …, 2022 - Elsevier
Abstract The European Human Biomonitoring Initiative (HBM4EU) assessed human
biomonitoring data on phthalates in children and adolescents, that were sampled between …
biomonitoring data on phthalates in children and adolescents, that were sampled between …
Toxicological Study of Human Exposure to Mixtures of Chemicals: Challenges and Approaches
Humans are exposed to highly diverse mixtures of complex and often unknown
compositions, which may adversely impact their health. There is a lack of guidance on how …
compositions, which may adversely impact their health. There is a lack of guidance on how …
Reproductive and Metabolic Health Following Exposure to Environmental Chemicals: Mechanistic Insights from Mammalian Models
The decline in human reproductive and metabolic health over the past 50 years is
associated with exposure to complex mixtures of anthropogenic environmental chemicals …
associated with exposure to complex mixtures of anthropogenic environmental chemicals …
Dose addition in the induction of craniofacial malformations in zebrafish embryos exposed to a complex mixture of food-relevant chemicals with dissimilar modes of …
LTM Van Der Ven, P Van Ommeren… - Environmental …, 2022 - ehp.niehs.nih.gov
Background: Humans are exposed to combinations of chemicals. In cumulative risk
assessment (CRA), regulatory bodies such as the European Food Safety Authority consider …
assessment (CRA), regulatory bodies such as the European Food Safety Authority consider …
DBP and BaP co-exposure induces kidney injury via promoting pyroptosis of renal tubular epithelial cells in rats
J Chen, Y Song, Y Liu, W Chen, Y Cen, M You, G Yang - Chemosphere, 2023 - Elsevier
Dibutyl phthalate (DBP) and benzo (a) pyrene (BaP) are widespread environmental and
foodborne contaminants that have detrimental effects on human health. Although people are …
foodborne contaminants that have detrimental effects on human health. Although people are …
Application of the Key Characteristics Framework to Identify Potential Breast Carcinogens Using Publicly Available in Vivo, in Vitro, and in Silico Data
Background: Chemicals that induce mammary tumors in rodents or activate estrogen or
progesterone signaling are likely to increase breast cancer (BC) risk. Identifying chemicals …
progesterone signaling are likely to increase breast cancer (BC) risk. Identifying chemicals …