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Strategies for the discovery of oxazolidinone antibacterial agents: Development and future perspectives
Oxazolidinones represent a significant class of synthetic bacterial protein synthesis
inhibitors that are primarily effective against Gram-positive bacteria. The commercial …
inhibitors that are primarily effective against Gram-positive bacteria. The commercial …
Antibiotic adjuvants against multidrug-resistant Gram-negative bacteria: important component of future antimicrobial therapy
W Li, Z Tao, M Zhou, H Jiang, L Wang, B Ji… - Microbiological …, 2024 - Elsevier
The swift emergence and propagation of multidrug-resistant (MDR) bacterial pathogens
constitute a tremendous global health crisis. Among these pathogens, the challenge of …
constitute a tremendous global health crisis. Among these pathogens, the challenge of …
Immunomodulator AS101 restores colistin susceptibility of clinical colistin-resistant Escherichia coli and Klebsiella pneumoniae in vitro and in vivo
H Liu, Y Zhang, Z Zhong, Y Gong, P Yu, Y Yang… - International Journal of …, 2024 - Elsevier
Objectives Colistin (COL) was once considered to be the last line of defence against
multidrug-resistant bacteria belonging to the family Enterobacteriaceae. Due to the misuse …
multidrug-resistant bacteria belonging to the family Enterobacteriaceae. Due to the misuse …
[HTML][HTML] The properties of linezolid, rifampicin, and vancomycin, as well as the mechanism of action of pentamidine, determine their synergy against Gram-negative …
M Tang, D Zhao, S Liu, X Zhang, Z Yao… - International Journal of …, 2023 - mdpi.com
Combining pentamidine with Gram-positive-targeting antibiotics has been proven to be a
promising strategy for treating infections from Gram-negative bacteria (GNB). However …
promising strategy for treating infections from Gram-negative bacteria (GNB). However …
Plumbagin enhances antimicrobial and anti-biofilm capacities of chlorhexidine against clinical Klebsiella pneumoniae while reducing resistance mutations
H Liu, H Chen, Z Ma, Y Zhang, S Zhang… - Microbiology …, 2024 - journals.asm.org
With the widespread misuse of disinfectants, the clinical susceptibility of Klebsiella
pneumoniae (K. pneumoniae) to chlorhexidine (CHX) has gradually diminished, posing …
pneumoniae (K. pneumoniae) to chlorhexidine (CHX) has gradually diminished, posing …
Azomycin Orchestrate Colistin-Resistant Enterobacter cloacae Complex's Colistin Resistance Reversal In Vitro and In Vivo
P Hu, H Chen, D Zhao, Z Ma, W Zeng… - ACS Infectious …, 2024 - ACS Publications
The Enterobacter cloacae complex (ECC) is a group of nosocomial pathogens that pose a
challenge in clinical treatment due to its intrinsic resistance and the ability to rapidly acquire …
challenge in clinical treatment due to its intrinsic resistance and the ability to rapidly acquire …
Colistin Enhances Antimicrobial Activity against colistin-resistant Klebsiella pneumoniae by combined with the Chinese herbal crocin-1
X Du, H Zhou, Y Wang, Y Liu, Y Huang, S Shi, M Xu… - 2023 - researchsquare.com
Background Colistin (COL) is one of the last-line antibiotics of defense against multidrug-
resistant (MDR) gram-negative bacteria However, colistin-resistant (Col-R) Klebsiella …
resistant (MDR) gram-negative bacteria However, colistin-resistant (Col-R) Klebsiella …