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Mobile genetic elements associated with antimicrobial resistance
Strains of bacteria resistant to antibiotics, particularly those that are multiresistant, are an
increasing major health care problem around the world. It is now abundantly clear that both …
increasing major health care problem around the world. It is now abundantly clear that both …
Antibiotic resistance in Pseudomonas aeruginosa–Mechanisms, epidemiology and evolution
Antibiotics are powerful drugs used in the treatment of bacterial infections. The inappropriate
use of these medicines has driven the dissemination of antibiotic resistance (AR) in most …
use of these medicines has driven the dissemination of antibiotic resistance (AR) in most …
Deciphering the mobility and bacterial hosts of antibiotic resistance genes under antibiotic selection pressure by metagenomic assembly and binning approaches
The presence of antibiotics can exert significant selection pressure on the emergence and
spread of antibiotic resistance genes (ARGs) and antibiotic resistant bacteria (ARB) …
spread of antibiotic resistance genes (ARGs) and antibiotic resistant bacteria (ARB) …
Co-occurrence of resistance genes to antibiotics, biocides and metals reveals novel insights into their co-selection potential
Background Antibacterial biocides and metals can co-select for antibiotic resistance when
bacteria harbour resistance or tolerance genes towards both types of compounds. Despite …
bacteria harbour resistance or tolerance genes towards both types of compounds. Despite …
Evolution of plasmid mobility: origin and fate of conjugative and nonconjugative plasmids
C Coluzzi, MP Garcillán-Barcia… - Molecular Biology …, 2022 - academic.oup.com
Conjugation drives the horizontal transfer of adaptive traits across prokaryotes. One-fourth of
the plasmids encode the functions necessary to conjugate autonomously, the others being …
the plasmids encode the functions necessary to conjugate autonomously, the others being …
Type IV secretion in Gram‐negative and Gram‐positive bacteria
Type IV secretion systems (T4SSs) are versatile multiprotein nanomachines spanning the
entire cell envelope in Gram‐negative and Gram‐positive bacteria. They play important …
entire cell envelope in Gram‐negative and Gram‐positive bacteria. They play important …
The role of integrative and conjugative elements in antibiotic resistance evolution
Mobile genetic elements (MGEs), such as plasmids and integrative and conjugative
elements (ICEs), are main drivers for the spread of antibiotic resistance (AR). Coevolution …
elements (ICEs), are main drivers for the spread of antibiotic resistance (AR). Coevolution …
Fungicide exposure accelerated horizontal transfer of antibiotic resistance genes via plasmid-mediated conjugation
Co-pollution of soil with pesticide residues and antibiotic resistance genes (ARGs) is
increasing due to the substantial usage of pesticides and organic fertilizers in greenhouse …
increasing due to the substantial usage of pesticides and organic fertilizers in greenhouse …
Phylogenetic background and habitat drive the genetic diversification of Escherichia coli
Escherichia coli is mostly a commensal of birds and mammals, including humans, where it
can act as an opportunistic pathogen. It is also found in water and sediments. We …
can act as an opportunistic pathogen. It is also found in water and sediments. We …
Identification of protein secretion systems in bacterial genomes
Bacteria with two cell membranes (diderms) have evolved complex systems for protein
secretion. These systems were extensively studied in some model bacteria, but the …
secretion. These systems were extensively studied in some model bacteria, but the …