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Unraveling aging from transcriptomics
Y Huang, S Zhu, S Yao, H Zhai, C Liu, JDJ Han - Trends in Genetics, 2024 - cell.com
Research into aging constitutes a pivotal endeavor aimed at elucidating the underlying
biological mechanisms governing aging and age-associated diseases, as well as promoting …
biological mechanisms governing aging and age-associated diseases, as well as promoting …
Molecular mechanisms of genotype-dependent lifespan variation mediated by caloric restriction: insight from wild yeast isolates
Caloric restriction (CR) is known to extend lifespan across different species and holds great
promise for preventing human age-onset pathologies. However, two major challenges exist …
promise for preventing human age-onset pathologies. However, two major challenges exist …
The Greenland shark (Somniosus microcephalus) genome provides insights into extreme longevity
Abstract The Greenland shark (Somniosus microcephalus) is the longest-lived vertebrate
known, with an estimated lifespan of∼ 400 years. Here, we present a chromosome-level …
known, with an estimated lifespan of∼ 400 years. Here, we present a chromosome-level …
Convergent evolution associated with the loss of developmental diapause may promote extended lifespan in bees
Diapause has long been proposed to play a significant role in the evolution of eusociality in
Hymenoptera. Recent studies have shown that shifts in the diapause stage precede social …
Hymenoptera. Recent studies have shown that shifts in the diapause stage precede social …
Genética y genómica de la longevidad y el envejecimiento
C Paz - Revista Médica-Científica CAMbios HECAM, 2023 - revistahcam.iess.gob.ec
El envejecimiento y la longevidad son procesos que involucran una serie de factores
genéticos, bioquímicos y ambientales. En esta revisión se tratan algunas cuestiones sobre …
genéticos, bioquímicos y ambientales. En esta revisión se tratan algunas cuestiones sobre …
Evolutionary paths to mammalian longevity through the lens of gene expression
The natural variation in mammalian longevity and its underlying mechanisms remain an
active area of aging research. In the latest issue of The EMBO Journal, Liu et al (2023) …
active area of aging research. In the latest issue of The EMBO Journal, Liu et al (2023) …
[HTML][HTML] Comparison of Alternative Splicing Landscapes Revealed by Long-Read Sequencing in Hepatocyte-Derived HepG2 and Huh7 Cultured Cells and Human …
A Kozlova, E Sarygina, K Deinichenko, S Radko… - Biology, 2023 - mdpi.com
Simple Summary In this study, we evaluated the differences in the alternative splicing (AS)
profiles between normal liver tissue, HepG2 malignant cells, and Huh7 malignant cells using …
profiles between normal liver tissue, HepG2 malignant cells, and Huh7 malignant cells using …
Insight from Wild Yeast Isolates into the Molecular Mechanisms of Lifespan Variation Mediated by Caloric Restriction.
Caloric restriction (CR) is known to extend lifespan across different species and holds great
promise for preventing human age-onset pathologies. However, two major challenges exist …
promise for preventing human age-onset pathologies. However, two major challenges exist …
[PDF][PDF] Proximate Causes of Ageing Are Likely Evolutionarily Bound and Appropriate Countermeasure Design Requires New Approaches
L Slade, T Etheridge, N Szewczyk - 2024 - preprints.org
Understanding mechanisms of ageing remains a complex challenge for biogerontologists,
but recent adaptations of evolutionary ageing theories offer a compelling lens in which to …
but recent adaptations of evolutionary ageing theories offer a compelling lens in which to …
[PDF][PDF] Molecular Mechanisms of Genotype-Dependent Lifespan Variation Mediated by Caloric
Molecular Mechanisms of Genotype-Dependent Lifespan Variation Mediated by Caloric
Restriction: Insight from Wild Yeast Isolates Page 1 1 Molecular Mechanisms of Genotype-Dependent …
Restriction: Insight from Wild Yeast Isolates Page 1 1 Molecular Mechanisms of Genotype-Dependent …