Internal membrane bound structures sequester all genetic material in eukaryotic cells. The
most prominent of these structures is the nucleus, which is bounded by a double membrane …

The pathway from gene activation in the nucleus to mRNA translation and decay at specific
locations in the cytoplasm is both streamlined and highly interconnected. This review …

Nuclear pore complexes (NPCs) are vital to nuclear–cytoplasmic communication in
eukaryotes. The yeast NPC‐associated TREX‐2 complex, also known as the Thp1–Sac3 …

Epigenetics and epigenomic medicine encompass a new science of brain and behavior that
are already providing unique insights into the mechanisms underlying brain development …

Adaptive variation tends to emerge clinally along environmental gradients or discretely
among habitats with limited connectivity. However, in Atlantic killifish (Fundulus heteroclitus) …

Exchange of macromolecules between the nucleus and cytoplasm is a key regulatory event
in the expression of a cell's genome. This exchange requires a dedicated transport …

Many genes in Saccharomyces cerevisiae are recruited to the nuclear periphery after
transcriptional activation. We have identified two gene recruitment sequences (GRS I and II) …

DNA methylation was once considered to be a static epigenetic modification whose primary
function was restricted to directing the development of cellular phenotype. However, it is now …

The diffusion coefficient of the transcription factor LacI within living Escherichia coli has been
measured directly by in vivo tracking to be D= 0.4 μ m2/s. At this rate, simple models of …

This work examines the involvement of chromatin loo** in the transcriptional regulation of
two epialleles of the maize (Zea mays) b1 gene, BI and B'. These two epialleles are tissue …