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Polymer nanoparticles for the intravenous delivery of anticancer drugs: the checkpoints on the road from the synthesis to clinical translation
In this review article we discuss some of the key aspects concerning the development of a
polymer-based nanoparticle formulation for intravenous drug delivery. Since numerous …
polymer-based nanoparticle formulation for intravenous drug delivery. Since numerous …
Strategies to combine ROP with ATRP or RAFT polymerization for the synthesis of biodegradable polymeric nanoparticles for biomedical applications
The architecture, composition and molecular weight (MW) of polymers and copolymers
made via free radical polymerization are important parameters that affect the end-use of both …
made via free radical polymerization are important parameters that affect the end-use of both …
In situ spectroscopic studies of highly transparent nanoparticle dispersions enable assessment of trithiocarbonate chain-end fidelity during RAFT dispersion …
EJ Cornel, S van Meurs, T Smith… - Journal of the …, 2018 - ACS Publications
We report the synthesis of highly transparent poly (stearyl methacrylate)-poly (2, 2, 2-
trifluoroethyl methacrylate)(PSMA–PTFEMA) diblock copolymer nanoparticles via …
trifluoroethyl methacrylate)(PSMA–PTFEMA) diblock copolymer nanoparticles via …
Cathepsin B-responsive prodrugs for cancer-targeted therapy: Recent advances and progress for clinical translation
The cathepsin B-responsive prodrugs are promising strategies to reduce the serious
adverse effects of anticancer drugs by improving the cancer selectivity that can be …
adverse effects of anticancer drugs by improving the cancer selectivity that can be …
HPMA-based polymeric conjugates in anticancer therapeutics
Highlights•HPMA (N-2-hydroxypropylmethacrylamide) is an emerging polymeric alternative
for drug delivery applications.•HPMA can be potentially conjugated to develop copolymers …
for drug delivery applications.•HPMA can be potentially conjugated to develop copolymers …
Current trends in the development of HPMA-based block copolymeric nanoparticles for their application in drug delivery
Abstract N-(2-hydroxypropyl) methacrylamide-based block copolymers (pHPMA) have
received attention due to their hydrophilicity, non-immunogenicity, biocompatibility and …
received attention due to their hydrophilicity, non-immunogenicity, biocompatibility and …
pH-responsive polymeric nanoparticles with tunable sizes for targeted drug delivery
Biodegradable nanoparticles (NPs) have shown great promise as intracellular imaging
probes, nanocarriers and drug delivery vehicles. In this study, we designed and prepared …
probes, nanocarriers and drug delivery vehicles. In this study, we designed and prepared …
Thermoresponsive Modular Nano-Objects Via RAFT Dispersion Polymerization in a Non-Polar Solvent
Thermoresponsive polymer nano-objects able to dynamically change their morphology in
response to modifications in the local temperature are finding growing attention for …
response to modifications in the local temperature are finding growing attention for …
Valorisation of glycerol and CO2 to produce biodegradable polymer nanoparticles with a high percentage of bio-based components
The biodiesel industry has grown rapidly in the last years, leading to the production of 88
000 tons of waste glycerol in 2018. Glycerol is a bio-derived molecule already exploited in …
000 tons of waste glycerol in 2018. Glycerol is a bio-derived molecule already exploited in …
Sequential post-polymerization modification of a pentafluorophenyl ester-containing homopolymer: a convenient route to effective pH-responsive nanocarriers for …
Y Pinyakit, T Palaga, S Kiatkamjornwong… - Journal of Materials …, 2020 - pubs.rsc.org
Recently, pH-responsive polymeric micelles have gained significant attention as effective
carriers for anti-cancer drug delivery. Herein, pH-responsive polymeric micelles were …
carriers for anti-cancer drug delivery. Herein, pH-responsive polymeric micelles were …