Actin dynamics, architecture, and mechanics in cell motility

L Blanchoin, R Boujemaa-Paterski… - Physiological …, 2014 - journals.physiology.org
Tight coupling between biochemical and mechanical properties of the actin cytoskeleton
drives a large range of cellular processes including polarity establishment, morphogenesis …

Active matter at the interface between materials science and cell biology

D Needleman, Z Dogic - Nature reviews materials, 2017 - nature.com
The remarkable processes that characterize living organisms, such as motility, self-healing
and reproduction, are fuelled by a continuous injection of energy at the microscale. The field …

A fluorescent membrane tension probe

A Colom, E Derivery, S Soleimanpour, C Tomba… - Nature …, 2018 - nature.com
Cells and organelles are delimited by lipid bilayers in which high deformability is essential to
many cell processes, including motility, endocytosis and cell division. Membrane tension is …

Active gel physics

J Prost, F Jülicher, JF Joanny - Nature physics, 2015 - nature.com
The mechanical behaviour of cells is largely controlled by a structure that is fundamentally
out of thermodynamic equilibrium: a network of crosslinked filaments subjected to the action …

Forcing cells into shape: the mechanics of actomyosin contractility

M Murrell, PW Oakes, M Lenz, ML Gardel - Nature reviews Molecular …, 2015 - nature.com
Actomyosin-mediated contractility is a highly conserved mechanism for generating
mechanical stress in animal cells and underlies muscle contraction, cell migration, cell …

Quantifying forces in cell biology

P Roca-Cusachs, V Conte, X Trepat - Nature cell biology, 2017 - nature.com
Cells exert, sense, and respond to physical forces through an astounding diversity of
mechanisms. Here we review recently developed tools to quantify the forces generated by …

Actin cortex mechanics and cellular morphogenesis

G Salbreux, G Charras, E Paluch - Trends in cell biology, 2012 - cell.com
The cortex is a thin, crosslinked actin network lying immediately beneath the plasma
membrane of animal cells. Myosin motors exert contractile forces in the meshwork. Because …

The actin cortex at a glance

P Chugh, EK Paluch - Journal of cell science, 2018 - journals.biologists.com
Precisely controlled cell deformations are key to cell migration, division and tissue
morphogenesis, and have been implicated in cell differentiation during development, as well …

Actin cortex architecture regulates cell surface tension

P Chugh, AG Clark, MB Smith, DAD Cassani… - Nature cell …, 2017 - nature.com
Animal cell shape is largely determined by the cortex, a thin actin network underlying the
plasma membrane in which myosin-driven stresses generate contractile tension. Tension …

Nonequilibrium physics in biology

X Fang, K Kruse, T Lu, J Wang - Reviews of Modern Physics, 2019 - APS
Life is characterized by a myriad of complex dynamic processes allowing organisms to grow,
reproduce, and evolve. Physical approaches for describing systems out of thermodynamic …