The impacts of H. pylori virulence factors on the development of gastroduodenal diseases

WL Chang, YC Yeh, BS Sheu - Journal of biomedical science, 2018 - Springer
Although most H. pylori infectors are asymptomatic, some may develop serious disease,
such as gastric adenocarcinoma, gastric high-grade B cell lymphoma and peptic ulcer …

Helicobacter pylori Virulence Factors Exploiting Gastric Colonization and its Pathogenicity

S Ansari, Y Yamaoka - Toxins, 2019 - mdpi.com
Helicobacter pylori colonizes the gastric epithelial cells of at least half of the world's
population, and it is the strongest risk factor for develo** gastric complications like chronic …

Helicobacter pylori virulence genes

A Šterbenc, E Jarc, M Poljak… - World journal of …, 2019 - pmc.ncbi.nlm.nih.gov
Helicobacter pylori (H. pylori) is one of the most important human pathogens, infecting
approximately half of the global population. Despite its high prevalence, only a subset of H …

Helicobacter pylori: gastric cancer and beyond

DB Polk, RM Peek Jr - Nature reviews cancer, 2010 - nature.com
Helicobacter pylori is the dominant species of the human gastric microbiome, and
colonization causes a persistent inflammatory response. H. pylori-induced gastritis is the …

Pathogenesis of Helicobacter pylori Infection

JG Kusters, AHM Van Vliet… - Clinical microbiology …, 2006 - journals.asm.org
Helicobacter pylori is the first formally recognized bacterial carcinogen and is one of the
most successful human pathogens, as over half of the world's population is colonized with …

Mechanisms of disease: Helicobacter pylori virulence factors

Y Yamaoka - Nature reviews Gastroenterology & hepatology, 2010 - nature.com
Helicobacter pylori plays an essential role in the development of various gastroduodenal
diseases; however, only a small proportion of people infected with H. pylori develop these …

Peptic ulcer disease

P Malfertheiner, FKL Chan, KEL McColl - The lancet, 2009 - thelancet.com
Peptic ulcer disease had a tremendous effect on morbidity and mortality until the last
decades of the 20th century, when epidemiological trends started to point to an impressive …

Helicobacter pylori in health and disease

TL Cover, MJ Blaser - Gastroenterology, 2009 - Elsevier
Helicobacter pylori is highly adapted for colonization of the human stomach and is present in
about half of the human population. When present, H pylori is usually the numerically …

Virulence of Helicobacter pylori outer membrane proteins: an updated review

C Xu, DM Soyfoo, Y Wu, S Xu - European Journal of Clinical Microbiology …, 2020 - Springer
Helicobacter pylori (H. pylori) infection is associated with some gastric diseases, such as
gastritis, peptic ulcer, and gastric cancer. CagA and VacA are known virulence factors of H …

Pathogenesis and clinical management of Helicobacter pylori gastric infection

BB de Brito, FAF da Silva, AS Soares… - World journal of …, 2019 - pmc.ncbi.nlm.nih.gov
Helicobacter pylori (H. pylori) is a gram-negative bacterium that infects approximately 4.4
billion individuals worldwide. However, its prevalence varies among different geographic …