Cancer stem cells (CSCs), a small subset of cells in tumors that are characterized by self-
renewal and continuous proliferation, lead to tumorigenesis, metastasis, and maintain tumor …

Ongoing research has revealed that the existence of cancer stem cells (CSCs) is one of the
biggest obstacles in the current cancer therapy. CSCs make an influential function in tumor …

Immune escape is a hallmark of cancer. The dynamic and heterogeneous tumour
microenvironment (TME) causes insufficient infiltration and poor efficacy of natural killer (NK) …

Cancer stem cells (CSCs) have emerged as key contributors to tumor initiation, growth, and
metastasis. In addition, CSCs play a significant role in inducing immune evasion, thereby …

Cancer stem cells (CSCs) have important roles in tumour development, relapse and
metastasis; the intrinsic self-renewal characteristics and tumorigenic properties of these cells …

Circulating tumor cells (CTCs) are the seeds of distant metastasis, and the number of CTCs
detected in the blood of cancer patients is associated with a worse prognosis. CTCs face …

Patients with acute myeloid leukaemia (AML) often achieve remission after therapy, but
subsequently die of relapse that is driven by chemotherapy-resistant leukaemic stem cells …

Cancer stem cells (CSCs) are heterogeneous, possess self-renewal attributes, and
orchestrate important crosstalk in tumors. We propose that the CSC state represents" …

Metastatic spread of tumour cells is the main cause of cancer-related deaths. Understanding
the mechanisms of tumour-cell dissemination has, therefore, become an important focus for …

Cancer stem cells (CSCs), also known as tumor‐initiating cells (TICs), are elucidated as
cells that can perpetuate themselves via autorestoration. These cells are highly resistant to …