Importance Malignant primary brain tumors cause more than 15 000 deaths per year in the
United States. The annual incidence of primary malignant brain tumors is approximately 7 …

Isocitrate dehydrogenase (IDH) mutant gliomas are the most common adult, malignant
primary brain tumors diagnosed in patients younger than 50, constituting an important cause …

Brain metastases occur commonly in patients with advanced solid malignancies. Yet, less is
known about brain metastases than cancer-related entities of similar incidence. Advances in …

Tumor-related epilepsy (TRE) is a frequent and major consequence of brain tumors.
Management of TRE is required throughout the course of disease and a deep …

Background This systematic review provides updated insights, from the published literature
in the past 5 years, based on the 2017 European Association of Neuro-Oncology (EANO) …

Purpose The extent of resection (EOR) is an independent prognostic factor for overall
survival (OS) in adult patients with Glioma Grade 4 (GG4). The aim of the neuro-oncology …

Central nervous system (CNS) tumor patients commonly undergo multimodality treatment in
the course of their disease. Adverse effects and complications from these interventions have …

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Seizures are among the most common clinical signs in people with glioblastoma. Advances
over the past 5 years, including new clinical trial data, have increased the understanding of …

Simple Summary Patients with lung cancer have high rates of brain metastasis (BM).
Despite available therapies, patient prognosis is poor. Studies have shown genetic …