Advancing biosensors with machine learning

F Cui, Y Yue, Y Zhang, Z Zhang, HS Zhou - ACS sensors, 2020 - ACS Publications
Chemometrics play a critical role in biosensors-based detection, analysis, and diagnosis.
Nowadays, as a branch of artificial intelligence (AI), machine learning (ML) have achieved …

[HTML][HTML] Deep learning methods in protein structure prediction

M Torrisi, G Pollastri, Q Le - Computational and structural biotechnology …, 2020 - Elsevier
Abstract Protein Structure Prediction is a central topic in Structural Bioinformatics. Since
the'60s statistical methods, followed by increasingly complex Machine Learning and recently …

Conformational ensembles of the human intrinsically disordered proteome

G Tesei, AI Trolle, N Jonsson, J Betz, FE Knudsen… - Nature, 2024 - nature.com
Intrinsically disordered proteins and regions (collectively, IDRs) are pervasive across
proteomes in all kingdoms of life, help to shape biological functions and are involved in …

BioSeq-BLM: a platform for analyzing DNA, RNA and protein sequences based on biological language models

HL Li, YH Pang, B Liu - Nucleic acids research, 2021 - academic.oup.com
In order to uncover the meanings of 'book of life', 155 different biological language models
(BLMs) for DNA, RNA and protein sequence analysis are discussed in this study, which are …

A completely reimplemented MPI bioinformatics toolkit with a new HHpred server at its core

L Zimmermann, A Stephens, SZ Nam, D Rau… - Journal of molecular …, 2018 - Elsevier
Abstract The MPI Bioinformatics Toolkit (https://toolkit. tuebingen. mpg. de) is a free, one-stop
web service for protein bioinformatic analysis. It currently offers 34 interconnected external …

Systematic identification of conditionally folded intrinsically disordered regions by AlphaFold2

TR Alderson, I Pritišanac, Đ Kolarić, AM Moses… - Proceedings of the …, 2023 - pnas.org
The AlphaFold Protein Structure Database contains predicted structures for millions of
proteins. For the majority of human proteins that contain intrinsically disordered regions …

iLearnPlus: a comprehensive and automated machine-learning platform for nucleic acid and protein sequence analysis, prediction and visualization

Z Chen, P Zhao, C Li, F Li, D **ang… - Nucleic acids …, 2021 - academic.oup.com
Sequence-based analysis and prediction are fundamental bioinformatic tasks that facilitate
understanding of the sequence (-structure)-function paradigm for DNAs, RNAs and proteins …

A short-term traffic flow prediction model based on an improved gate recurrent unit neural network

W Shu, K Cai, NN **ong - IEEE Transactions on Intelligent …, 2021 - ieeexplore.ieee.org
With the increasing demand for intelligent transportation systems, short-term traffic flow
prediction has become an important research direction. The memory unit of a Long Short …

NetSurfP‐2.0: Improved prediction of protein structural features by integrated deep learning

MS Klausen, MC Jespersen, H Nielsen… - Proteins: Structure …, 2019 - Wiley Online Library
The ability to predict local structural features of a protein from the primary sequence is of
paramount importance for unraveling its function in absence of experimental structural …

Metapredict: a fast, accurate, and easy-to-use predictor of consensus disorder and structure

RJ Emenecker, D Griffith, AS Holehouse - Biophysical journal, 2021 - cell.com
Intrinsically disordered proteins and protein regions make up a substantial fraction of many
proteomes in which they play a wide variety of essential roles. A critical first step in …