Herpesviruses replicate their DNA and package this DNA into capsids in the nucleus. These
capsids then face substantial obstacles to their release from cells. Unlike other DNA viruses …

Alphaherpesviruses like herpes simplex virus are large DNA viruses characterized by their
ability to establish lifelong latent infection in neurons. As for all herpesviruses …

The order Herpesvirales contains viruses infecting animals from molluscs to men with a
common virion morphology which have been classified into the families Herpesviridae …

INTRODUCTION Since Hippocrates first described the cutaneous spreading of herpes
simplex lesions, many other diseases—chickenpox, infectious mononucleosis …

The herpes simplex virus type 1 (HSV-1) genome is contained in a capsid wrapped by a
complex tegument layer and an external envelope. The poorly defined tegument plays a …

What could be a better way to study virus trafficking than'miniaturizing oneself'and'taking a
ride with the virus particle'on its journey into the cell? Single-virus tracking in living cells …

The nucleoplasm, the cytosol, the inside of virions, and again the cytosol comprise the world
in which the capsids of alphaherpesviruses encounter viral and host proteins that support or …

Microtubule-mediated transport of macromolecules and organelles (also known as" cargo")
is essential for cells to function. Deficiencies in cytoplasmic transport are frequently …

Herpes virions are amongst the most complex virus particles: they comprise in excess of
thirty virally encoded proteins, and also contain cellular components. Capsid formation and …

It is now clear that transport on microtubules by dynein and kinesin family motors has an
important if not critical role in the replication and spread of many different viruses …