Diabetes mellitus (DM) is associated with several microvascular and macrovascular
complications, such as retinopathy, nephropathy, neuropathy, and cardiovascular diseases …

The current unidimensional paradigm of kidney disease detection is incompatible with the
complexity and heterogeneity of renal pathology. The diagnosis of kidney disease has …

Diabetic nephropathy is a common kidney condition in patients with diabetes mellitus, which
can result in renal failure. Pyroptosis, the process of pro-inflammatory programmed cell …

Cytokines act as pleiotropic polypeptides regulating inflammatory and immune responses
through actions on cells. They provide important signals in the pathophysiology of a range of …

Probably, the most paradigmatic example of diabetic complication is diabetic nephropathy,
which is the largest single cause of end‐stage renal disease and a medical catastrophe of …

Context: Recent developments indicate that pathophysiological mechanisms leading to β-
cell damage, insulin resistance, and the vascular complications of diabetes include an …

Diabetic neuropathies (DNs) are one of the most prevalent chronic complications of diabetes
and a major cause of disability, high mortality, and poor quality of life. Given the complex …

Background Although diabetic kidney disease demonstrates both familial clustering and
single nucleotide polymorphism heritability, the specific genetic factors influencing risk …

Biomarkers of diverse pathophysiologic mechanisms may improve risk stratification for
incident or progressive diabetic kidney disease (DKD) in persons with type 2 diabetes. To …

Hyperglycemia-mediated oxidative stress plays a crucial role in the progression of diabetic
nephropathy. Hence, the present study was hypothesized to explore the renoprotective …