Browsing the oldest antioxidant enzyme: catalase and its multiple regulation in cancer
M Galasso, S Gambino, MG Romanelli… - Free Radical Biology …, 2021 - Elsevier
Aerobic organisms possess numerous antioxidant enzymatic families, including catalases,
superoxide dismutases (SODs), peroxiredoxins (PRDXs), and glutathione peroxidases …
superoxide dismutases (SODs), peroxiredoxins (PRDXs), and glutathione peroxidases …
CSC radioresistance: a therapeutic challenge to improve radiotherapy effectiveness in cancer
Radiotherapy (RT) is a modality of oncologic treatment that can be used to treat
approximately 50% of all cancer patients either alone or in combination with other treatment …
approximately 50% of all cancer patients either alone or in combination with other treatment …
MicroRNAs and their role on fish oxidative stress during xenobiotic environmental exposures
There is a growing global concern about the health implications of xenobiotics, which have
harmful effects to both humans and wildlife. Among them, teleost fish are known as very …
harmful effects to both humans and wildlife. Among them, teleost fish are known as very …
Luteolin inhibits breast cancer stemness and enhances chemosensitivity through the Nrf2-mediated pathway
KJ Tsai, HY Tsai, CC Tsai, TY Chen, TH Hsieh… - Molecules, 2021 - mdpi.com
Cancer stem cells (CSCs) are subpopulations of tumor masses with unique abilities in self-
renewal, stemness maintenance, drug resistance, and the promotion of cancer recurrence …
renewal, stemness maintenance, drug resistance, and the promotion of cancer recurrence …
Roles of peroxiredoxins in cancer, neurodegenerative diseases and inflammatory diseases
MH Park, MR Jo, YR Kim, CK Lee, JT Hong - Pharmacology & Therapeutics, 2016 - Elsevier
Peroxiredoxins (PRDXs) are antioxidant enzymes, known to catalyze peroxide reduction to
balance cellular hydrogen peroxide (H 2 O 2) levels, which are essential for cell signaling …
balance cellular hydrogen peroxide (H 2 O 2) levels, which are essential for cell signaling …
[HTML][HTML] Micromanaging aerobic respiration and glycolysis in cancer cells
Background Cancer cells possess a common metabolic phenotype, rewiring their metabolic
pathways from mitochondrial oxidative phosphorylation to aerobic glycolysis and anabolic …
pathways from mitochondrial oxidative phosphorylation to aerobic glycolysis and anabolic …
[HTML][HTML] Redox regulation of cell state and fate
BWL Lee, P Ghode, DST Ong - Redox biology, 2019 - Elsevier
The failure in effective cancer treatment is thought to be attributed to a subpopulation of
tumor cells with stem cell-like properties. These cancer stem cells (CSCs) are intimately …
tumor cells with stem cell-like properties. These cancer stem cells (CSCs) are intimately …
The autophagy inhibitor chloroquine targets cancer stem cells in triple negative breast cancer by inducing mitochondrial damage and impairing DNA break repair
Triple negative breast cancer (TNBC), characterized by an abundance of treatment-resistant
breast cancer stem cells (CSCs), has a poorer prognosis than other types of breast cancers …
breast cancer stem cells (CSCs), has a poorer prognosis than other types of breast cancers …
Cancer stem cells and signaling pathways in radioresistance
L Chang, P Graham, J Hao, J Ni, J Deng, J Bucci… - …, 2015 - pmc.ncbi.nlm.nih.gov
Radiation therapy (RT) is one of the most important strategies in cancer treatment.
Radioresistance (the failure to RT) results in locoregional recurrence and metastasis …
Radioresistance (the failure to RT) results in locoregional recurrence and metastasis …
Microenvironmental reactive oxygen species in colorectal cancer: involved processes and therapeutic opportunities
Simple Summary Colorectal cancer is a disease associated with a high mortality rate. During
the tumorigenic process, several factors and signaling molecules produced by tumor cells …
the tumorigenic process, several factors and signaling molecules produced by tumor cells …