Quantitative and logic modelling of molecular and gene networks
N Le Novere - Nature Reviews Genetics, 2015 - nature.com
Behaviours of complex biomolecular systems are often irreducible to the elementary
properties of their individual components. Explanatory and predictive mathematical models …
properties of their individual components. Explanatory and predictive mathematical models …
Single-cell network biology for resolving cellular heterogeneity in human diseases
Understanding cellular heterogeneity is the holy grail of biology and medicine. Cells
harboring identical genomes show a wide variety of behaviors in multicellular organisms …
harboring identical genomes show a wide variety of behaviors in multicellular organisms …
The recurrent architecture of tumour initiation, progression and drug sensitivity
Recent studies across multiple tumour types are starting to reveal a recurrent regulatory
architecture in which genomic alterations cluster upstream of functional master regulator …
architecture in which genomic alterations cluster upstream of functional master regulator …
A review on the computational approaches for gene regulatory network construction
Many biological research areas such as drug design require gene regulatory networks to
provide clear insight and understanding of the cellular process in living cells. This is …
provide clear insight and understanding of the cellular process in living cells. This is …
Gene regulatory network reconstruction: harnessing the power of single-cell multi-omic data
Inferring gene regulatory networks (GRNs) is a fundamental challenge in biology that aims
to unravel the complex relationships between genes and their regulators. Deciphering these …
to unravel the complex relationships between genes and their regulators. Deciphering these …
The interdependency and co-regulation of the vitamin D and cholesterol metabolism
T Warren, R McAllister, A Morgan, TS Rai, V McGilligan… - Cells, 2021 - mdpi.com
Vitamin D and cholesterol metabolism overlap significantly in the pathways that contribute to
their biosynthesis. However, our understanding of their independent and co-regulation is …
their biosynthesis. However, our understanding of their independent and co-regulation is …
[KİTAP][B] Dynamics and Bifurcation in Networks: Theory and Applications of Coupled Differential Equations
M Golubitsky, I Stewart - 2023 - SIAM
The biologist JBS Haldane, when asked what we can learn about the Creator by examining
the world, is said to have replied “an inordinate fondness for beetles”[705]. Today's …
the world, is said to have replied “an inordinate fondness for beetles”[705]. Today's …
A survey of gene regulatory networks modelling methods: from differential equations, to Boolean and qualitative bioinspired models
Abstract Gene Regulatory Networks (GRNs) represent the interactions among genes
regulating the activation of specific cell functionalities, such as reception of (chemical) …
regulating the activation of specific cell functionalities, such as reception of (chemical) …
[KİTAP][B] Biomolecular information processing: from logic systems to smart sensors and actuators
E Katz - 2013 - books.google.com
Edited by a renowned and much cited chemist, this book covers the whole span of molecular
computers that are based on biomolecules. The contributions by all the major scientists in …
computers that are based on biomolecules. The contributions by all the major scientists in …
Dynamics and bifurcations in genetic circuits with fibration symmetries
Circuit building blocks of gene regulatory networks (GRN) have been identified through the
fibration symmetries of the underlying biological graph. Here, we analyse analytically six of …
fibration symmetries of the underlying biological graph. Here, we analyse analytically six of …