[HTML][HTML] Total neoadjuvant therapy in rectal cancer: the evidence and expectations
L Boublikova, A Novakova, J Simsa… - Critical Reviews in …, 2023 - Elsevier
Current management of locally advanced rectal cancer achieves high cure rates, distant
metastatic spread being the main cause of patients' death. Total neoadjuvant therapy (TNT) …
metastatic spread being the main cause of patients' death. Total neoadjuvant therapy (TNT) …
Recent Advances in Therapeutic Strategies to Improve Colorectal Cancer Treatment
WH Gmeiner - Cancers, 2024 - mdpi.com
Simple Summary Colorectal cancer is a leading cause of cancer mortality, and its incidence
is rapidly increasing worldwide. Colorectal cancer is considered a single entity based on …
is rapidly increasing worldwide. Colorectal cancer is considered a single entity based on …
Impact of KRAS mutations and co-mutations on clinical outcomes in pancreatic ductal adenocarcinoma
The relevance of KRAS mutation alleles to clinical outcome remains inconclusive in
pancreatic adenocarcinoma (PDAC). We conducted a retrospective study of 803 patients …
pancreatic adenocarcinoma (PDAC). We conducted a retrospective study of 803 patients …
Molecular, socioeconomic, and clinical factors affecting racial and ethnic disparities in colorectal cancer survival
Importance Disparity in overall survival (OS) and differences in the frequency of driver gene
variants by race and ethnicity have been separately observed in patients with colorectal …
variants by race and ethnicity have been separately observed in patients with colorectal …
Serum tumor markers and outcomes in patients with Appendiceal Adenocarcinoma
Importance Serum tumor markers carcinoembryonic antigen (CEA), carbohydrate antigen 19-
9 (CA19-9), and cancer antigen 125 (CA125) have been useful in the management of …
9 (CA19-9), and cancer antigen 125 (CA125) have been useful in the management of …
The national burden of colorectal cancer in the United States from 1990 to 2019
Simple Summary Colorectal cancer (CRC) is a significant global health concern, ranking as
the second leading cause of cancer-related deaths. Despite an overall decline in CRC rates …
the second leading cause of cancer-related deaths. Despite an overall decline in CRC rates …
Elevated BEAN1 expression correlates with poor prognosis, immune evasion, and chemotherapy resistance in rectal adenocarcinoma
T Shapaer, Y Chen, Y Pan, Z Wu, T Tang, Z Zhao… - Discover Oncology, 2024 - Springer
Background The BEAN1 gene, primarily studied in neurodegenerative diseases, has been
scarcely studied in the context of cancers. Our research examines BEAN1 expression …
scarcely studied in the context of cancers. Our research examines BEAN1 expression …
Enhanced therapeutic efficacy of the nanoscale fluoropyrimidine polymer CF10 in a rat colorectal cancer liver metastasis model
Simple Summary Liver metastases are a major cause of colorectal cancer mortality. To
combat this, chemotherapy is widely used but generally does not result in long-term survival …
combat this, chemotherapy is widely used but generally does not result in long-term survival …
[HTML][HTML] Precision Medicine for Metastatic Colorectal Cancer: Where Do We Stand?
Metastatic colorectal cancer is a leading cause of cancer-related death across the world.
The treatment paradigm has shifted away from systemic chemotherapy alone to include …
The treatment paradigm has shifted away from systemic chemotherapy alone to include …
Clinical Prediction Models for Prognosis of Colorectal Liver Metastases: A Comprehensive Review of Regression-Based and Machine Learning Models
Simple Summary Interest in stratification of prognosis for patients with colorectal liver
metastases is growing. Numerous clinical prediction models have been developed for this …
metastases is growing. Numerous clinical prediction models have been developed for this …