The human organic anion and cation transporters are classified within two SLC
superfamilies. Superfamily SLCO (formerly SLC21A) consists of organic anion transporting …

The biodistribution of approved gadolinium (Gd)‐based contrast agents (GBCAs) is
reviewed. After intravenous injection GBCAs distribute in the blood and the extracellular …

Organic anion transporting polypeptides (Oatps/OATPs) form a growing gene superfamily
and mediate transport of a wide spectrum of amphipathic organic solutes. Different …

1. The organic anion transporting polypeptides (humans OATP; other species Oatp) belong
to the SLCO gene superfamily of transporters and are twelve transmembrane domain …

Objectives: To investigate the ability of T1 map** of liver on gadolinium ethoxybenzyl
diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance …

Organic anion transporting polypeptides (OATPs) mediate the uptake of a broad range of
compounds into cells. Substrates for members of the OATP family include bile salts …

The vectorial secretion of bile salts from blood into bile is a major driving force for bile
formation. The basolateral hepatocyte membrane extracts bile salts from sinusoidal blood …

The purpose of this review is to outline recent trends in contrast agent development for
magnetic resonance imaging. Up to now, small molecular weight gadolinium chelates are …

Objectives The purpose of this study was to evaluate the usefulness of Gd-EOB-DTPA-
enhanced 3-T MRI to determine the hepatic functional reserve expressed by the model for …

The alterations of hepatobiliary transport that occur in cholestasis can be divided into
primary defects, such as mutations of transporter genes or acquired dysfunctions of transport …