Abstract Iron-sulfur (Fe–S) clusters are essential cofactors most commonly known for their
role mediating electron transfer within the mitochondrial respiratory chain. The Fe–S cluster …

Iron-sulfur (Fe/S) proteins are involved in a wide variety of cellular processes such as
enzymatic reactions, respiration, cofactor biosynthesis, ribosome biogenesis, regulation of …

Ferroptosis is a form of non-apoptotic cell death originally identified in cancer cells.
However, the key regulator of ferroptosis in mitochondria remains unknown. Here, we show …

We examined mouse models with altered adipocyte expression of mitoNEET, a protein
residing in the mitochondrial outer membrane, to probe its impact on mitochondrial function …

Although defects in intracellular calcium homeostasis are known to play a role in the
pathogenesis of Parkinson's disease (PD), the underlying molecular mechanisms remain …

Ethanol misuse is frequently associated with a multitude of profound medical conditions,
contributing to health-, individual-and social-related damage. A particularly dangerous threat …

Gene expression profiling can be used to uncover the mechanisms by which loci identified
through genome-wide association studies (GWAS) contribute to pathology,. Given that most …

Multiple avenues of research including epidemiology, molecular genetics and cell biology
have identified links between Parkinson's disease and type 2 diabetes mellitus. Several …

In addition to mitochondria, BCL‐2 is located at the endoplasmic reticulum (ER) where it is a
constituent of several distinct complexes. Here, we identify the BCL‐2‐interacting protein at …

MitoNEET is an outer mitochondrial membrane protein essential for sensing and regulation
of iron and reactive oxygen species (ROS) homeostasis. It is a key player in multiple human …